What clinical situations are associated with decreased levels of plasmin inhibitor? Elevated levels?

Congenital deficiencies are characterized by bleeding occurring some hours after the initial injury. Clotting and wound healing are usually normal, but the hemostatic plug is defective and breaks down prematurely. As a result of liver diseases and DIC, decreased levels of plasmin inhibitor can be observed. Increased levels of plasmin inhibitor have been reported during post-operative episodes.