Haematex GO-DOAC™ 4ml
$0.00
Go-DOAC™ Rapid DOAC Test is a simplified clotting test with high sensitivity for all DOACs (including dabigatran, apixaban, rivaroxaban, and edoxaban).
Go-DOAC™ test reagent is a modified phospholipid-rich Russells viper venom reagent with enhanced sensitivity to DOACs. Go-DOAC™ is resistant to most lupus inhibitors and heparins (up to 1u/ml) but is sensitive to warfarin and defects in the common coagulation pathway.
Direct oral anticoagulants (DOACs) include inhibitors of thrombin (eg. dabigatran) and factor Xa (eg. rivaroxaban, apixaban and edoxaban). The latter group is difficult to quantitate using current clotting methods, and expensive chromogenic assays are used for the individual agents.
The lupus anticoagulant-resistant dilute Russells viper venom test (dRVT-LR or “Confirm”) has been suggested as a possible test method for all the DOACs since it is very sensitive to both classes of these inhibitors in vitro and in vivo and is less affected by extraneous variables such as heparins or low factor VIII levels than other clotting tests.
Go-DOAC™ is compatible with Thrombin Time test on an analyzer and only takes two minutes, enabling rapid identification of DOACs for research use only.
The freeze dried reagent reconstitutes to 4mL and is stable for one year after hydration when stored at 2-8°C.