Emerging Biomarkers in Alcohol Associated Liver Disease
Posted: February 7, 2023
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Non-Invasive Biomarkers for Alcohol Associated Liver Disease Studies
Biomarkers of cell death and regeneration, inflammation, and immune response become useful tools as new potential Alcohol Associated Liver Disease (ALD) and Alcohol Associated Hepatitis (AH) treatment options are investigated. Serum biomarkers can provide valuable insights into:
- Disease severity and progression in ALD and AH research studies
- Mechanisms involved in ALD and AH pathogenesis
DiaPharma has the tools for ALD Research.
Measure hepatocyte apoptosis and/or necrosis with our Cytokeratin 18/Keratin 18 (CK18/K18) biomarkers:
- M30 Apoptosense® ccK18 ELISA
- Measures apoptosis
- M65® ELISA and M65® EpiDeath® K18 ELISA
- Measures total cell death
Additional Biomarkers of Interest:
- MMP Activity assays – MMP-2, MMP-8 and MMP-9 are potential markers of alcohol-associated liver cirrhosis
- WNT3A – marker of regeneration
- ERBB3 – levels are elevated during HCC
- Osteopontin (OPN) – important liver fibrosis and inflammatory biomarker
- Soluble CD163 (sCD163) – Macrophage-induced inflammation marker
- Complement Factors 3a/5a/C5b-9 – majority of complement components are produced in the liver and innate immune marker
- Total Collagen – measure total collagen in the liver without matrix effects
Also, ask us about the first commercial immunoassay kit to measure NETs in human plasma or serum on the market. Perfect for sepsis studies.
Visit diapharma.com for our comprehensive portfolio including biomarkers for Nonalcoholic Fatty Liver Disease (NAFLD) / Nonalcoholic Steatohepatitis (NASH) and Drug Induced Liver Injury (DILI).
All products are for research use only in the U.S. and Canada. Not for use in diagnostic procedures.
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DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069
Technical Support: 1.800.447.3846
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