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Technoview® rivaroxaban control high is a plasma control with a high concentration of rivaroxaban* (~300 ng/ml) for use as a quality control sample in research measurements of rivaroxaban. It is optimized for use with anti-Xa chromogenic assays and is frequently used in conjunction with the Technoview® rivaroxaban low control, the Technoview® rivaroxaban medium control and the Technoview® apixaban calibrator set in the Technochrom® anti-Xa chromogenic assay.
*Rivaroxaban is the active substance in Xarelto®.
Reagent | Size | Description |
CON H | 5 x 1 mL | Technoview® Rivaroxaban Control High, human plasma, lyophilized, ~300 ng/mL Rivaroxaban |
Please consult the lot specific batch table provided with the controls for the exact concentrations in ng/mL of each calibrator.
Stability after reconstitution: 18-25°C (open vial) / 48 hours, 2-8°C (closed vial) / 7 days.
Control material is lyophilized and prepared from pooled human citrated plasma supplemented with a high concentration of rivaroxaban. The plasma contains stabilizers but no bactericide additives. It is calibrated, using a high performance liquid chromatography-tandem mass spectrometry assay, against a rivaroxaban structural analogue.
Rivaroxaban (Xarelto®) is an oral direct factor Xa inhibitor drug. It is prescribed by a healthcare provider and can:
In most cases, rivaroxaban does not require routine monitoring. It typically prolongs clotting tests such as PT/INR and aPTT so it is best measured using anti-Xa chromogenic assays. Note that this control is for research use only in the US and Canada.
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