Measure True Beta Cell Dysfunction with TECO Intact Proinsulin

Posted: June 6, 2022

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When it comes to measuring pancreatic Beta cell function, go with the Pro!

TECO® Intact Proinsulin ELISA

Save time and guess work by selectively measuring only intact proinsulin.

Proinsulin is synthesized in pancreatic β-cells and secreted as insulin. Insulin resistance (IR) or hyperglycemia causes increased secretion and finally secretion disorder. Intact proinsulin levels in plasma then increase while insulin levels decrease. Elevated fasting intact proinsulin is a specific biomarker for β-cell dysfunction and insulin resistance.

The TECO® Intact Proinsulin ELISA measures intact proinsulin, providing a direct measure of pancreatic β-cell function.

Intact Proinsulin ELISA

Benefits of the TECO® Intact Proinsulin ELISA:

  • Reliable tool for Diabetes and Metabolic Syndrome research and drug development studies
  • Measures intact Proinsulin only
    • Intact Proinsulin is a direct measure of pancreatic Beta-cell function
    • Avoid the noise – Total Proinsulin also measures intact and stable cleavage fragments
    • Standardized against WHO reference 09/296
  • Assay time less than 2.5 hours means fast results – no need for overnight incubation
  • Sensitive and specific antibodies
  • Available exclusively in North America from DiaPharma

Explore our additional diabetes research markers to assist in drug development, including:

  • Anti- GAD
  • Anti-ZnT8
  • Anti- IA2

Visit diapharma.com for our comprehensive portfolio.

For research use only in the U.S. and Canada. Not for use in diagnostic procedures.


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