Are your patients properly anticoagulated?

Posted: January 16, 2024

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Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Measuring Warfarin in Patients

with a Lupus Anticoagulant

Throughout last year, the use of DOACs in patients with antiphospholipid antibody syndrome (aPS) has been debated. Here we address two key questions:

  • What are the options for monitoring a patient with the presence of a strong LA inhibitor, where INRs might be unreliable?
  • What test can measure the effect of warfarin to help ensure the patient is in therapeutic range?

The chromogenic Factor X assay can be used here to measure % Factor X (FX) levels. Chromogenic FX activity levels have shown utility for monitoring warfarin therapy in patients where INR is unreliable, such as in aPS.

The DiaPharma Factor X Kit is accessible, FDA cleared, and offered by reference labs across the U.S.

Visit to learn more.

Factor X, chromogenic Factor X assay

Reference: Rosborough T.K., Shepherd M.F. Unreliability of international normalized ratio for monitoring warfarin therapy in patients with lupus anticoagulant. Pharmacotherapy. 2004;24(7):838–842.

View our full portfolio of hemostasis and thrombosis assays at

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