Exploratory Biomarkers for Acute and Chronic Kidney Injury Studies

Posted: June 28, 2022

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Diapharma L-FABP NGAL Osteopontin alpha-GST Cystatin C RBP4 Anti-EHEC

Spotlight on Acute and Chronic Kidney Injury

Enhanced assays with improved sensitivity and specificity to assist in kidney disease studies

L-FABP ● NGAL ● Osteopontin ●

alpha-GST ● Cystatin C ● RBP4 ●


There are large gaps in the information that standard kidney markers, like serum creatinine, can provide in the context of kidney injury. Indication of risk level, etiology of damage or disease, treatment response, and outcomes are all areas that can be greatly improved upon. DiaPharma is proud to offer a unique and well characterized panel of kidney biomarkers that can be used to overcome these gaps. Our biomarkers include stress or damage markers that provide mechanistic information of sub-clinical levels of damage associated with chronic and acute kidney injury. From cardio-renal to diabetes studies, these biomarkers can provide earlier and more descriptive insight than the standard kidney markers.

Learn about our extensive line of mechanistic biomarker assays for drug development and drug safety studies.

Our knowledgeable scientists are happy to discuss our portfolio of biomarker assays.

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Biomarker Sample Type Description Available Assays Product #
Liver Fatty Acid Binding Protein (L-FABP) Urine Biomarker for proximal tubule damage Urinary L-FABP 006
Alpha Glutathione S-Transferase (α-GST) Urine Biomarker for acute proximal tubule injury TECO® alpha-GST TE1056
Neutrophil Gelatinase-Associated Lipocalin (NGAL) Urine Biomarker for acute global tubular injury Diapharma NGAL (96)
Diapharma NGAL (2 x 96)
IMD Lipocalin-2
Cystatin C (CysC) Serum plasma, or Urine Biomarker of glomerular filtration (serum CysC) and tubular dysfunction (urinary CysC) IMD Rapid Cystatin C 31241
Osteopontin (OPN) Urine Biomarker for global tubular injury Osteopontin
Osteopontin N-Half
Retinol Binding Protein 4 (RBP4) Urine Biomarker of proximal tubule function Retinol Binding Protein 4 (RBP4) 31060
Anti-EHEC O157:H7 IgM Serum, plasma Biomarker for the investigation of STEC-HUS and associated acute kidney injury Hycult EcHECk HK508
Sample Collection Tubes Urine Preserves urinary proteins. The 5 ml tubes are filled with 0.8 ml of buffer TECO® Urine Stabilizing Tubes TE1050

Research use only in the U.S. and Canada. Not for use in diagnostic procedures.

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