Exploratory Biomarkers for Acute and Chronic Kidney Injury Studies
Posted on: June 28, 2022
This is an archived edition of our email newsletter.
It’s Not Just Support. It’s Solutions.
Spotlight on Acute and Chronic Kidney Injury
Enhanced assays with improved sensitivity and specificity to assist in kidney disease studies
L-FABP ● NGAL ● Osteopontin ●
alpha-GST ● Cystatin C ● RBP4 ●
Anti-EHEC
There are large gaps in the information that standard kidney markers, like serum creatinine, can provide in the context of kidney injury. Indication of risk level, etiology of damage or disease, treatment response, and outcomes are all areas that can be greatly improved upon. DiaPharma is proud to offer a unique and well characterized panel of kidney biomarkers that can be used to overcome these gaps. Our biomarkers include stress or damage markers that provide mechanistic information of sub-clinical levels of damage associated with chronic and acute kidney injury. From cardio-renal to diabetes studies, these biomarkers can provide earlier and more descriptive insight than the standard kidney markers.
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Learn about our extensive line of mechanistic biomarker assays for drug development and drug safety studies. Our knowledgeable scientists are happy to discuss our portfolio of biomarker assays. |
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| Biomarker | Sample Type | Description | Available Assays | Product # |
| Liver Fatty Acid Binding Protein (L-FABP) | Urine | Biomarker for proximal tubule damage | Urinary L-FABP | 006 |
| Alpha Glutathione S-Transferase (α-GST) | Urine | Biomarker for acute proximal tubule injury | TECO® alpha-GST | TE1056 |
| Neutrophil Gelatinase-Associated Lipocalin (NGAL) | Urine | Biomarker for acute global tubular injury | Diapharma NGAL (96) Diapharma NGAL (2 x 96) IMD Lipocalin-2 |
DPG-NGAL DPG-2NGAL 31050 |
| Cystatin C (CysC) | Serum plasma, or Urine | Biomarker of glomerular filtration (serum CysC) and tubular dysfunction (urinary CysC) | IMD Rapid Cystatin C | 31241 |
| Osteopontin (OPN) | Urine | Biomarker for global tubular injury | Osteopontin Osteopontin N-Half |
DPG27158 DPG27258 |
| Retinol Binding Protein 4 (RBP4) | Urine | Biomarker of proximal tubule function | Retinol Binding Protein 4 (RBP4) | 31060 |
| Anti-EHEC O157:H7 IgM | Serum, plasma | Biomarker for the investigation of STEC-HUS and associated acute kidney injury | Hycult EcHECk | HK508 |
| Sample Collection Tubes | Urine | Preserves urinary proteins. The 5 ml tubes are filled with 0.8 ml of buffer | TECO® Urine Stabilizing Tubes | TE1050 |
Research use only in the U.S. and Canada. Not for use in diagnostic procedures.
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