Assays for your Gene Therapy Research in Rare Diseases

Posted: March 3, 2022

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Explore Assays for Gene Therapy and Cell Therapy Research in Rare Diseases

 

HEMOPHILIA A & B

  • Chromogenic FVIII – Coamatic® FVIII, Coatest® SP/SP4 FVIII
    • Sensitive and reproducible, featuring bovine factor reagents
  • Chromogenic FIX – ROX FIX*
    • Bringing chromogenic FIX testing into the next era with unsurpassed sensitivity

SICKLE CELL

DiaPharma offers a full panel of antibodies for detection of various types of hemoglobin.

  • Anti-Hemoglobin S antibodies
  • Anti-Hemoglobin F antibodies
    • Analyte Specific Reagents (ASR). Analytical and performance characteristics are not established.

HEREDITARY ANGIOEDEMA (HAE)

  • Technochrom® C1-INH*
    • Chromogenic C1 Esterase Inhibitor (C1-INH) activity
    • Easy, automatable, simple and fast assay for chromogenic determination of C1-INH activity in plasma or concentrates

Thrombin Generation Testing*

  • Technothrombin® TGA
  • Ceveron®* for TGA and all-in-one coagulation analyzer

CYSTIC FIBROSIS

  • ProAxsis ProteaseTag™ Active Neutrophil Elastase*
  • ProAxsis NEATstik® Rapid NE Activity*
    • Robust assay measures only active NE
    • Available in 2 formats – standard and lateral flow, providing NE detection limits ranging from 7.2 – 1000 ng/ml.

HEPATOTOXICITY

  • Cytokeratin 18 (CK18) M30® Apoptosense* and M65® ELISA*
    • Serum biomarkers that measure hepatocyte death (apoptosis and necrosis)
    • Increased organ specificity for early detection of liver injury
  • M65® EpiRat ELISA*
    • New tool for translational research
    • Measure hepatocyte death in rat models
  • Osteopontin, alpha-GST, N-GAL, L-FABP, Cystatin C* also available

*For research use only. Not for use in diagnostic procedures.


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