Collagen Related Peptide-A (CRP-A™)
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Synthetic collagen related peptide A (CRP-A™).
- Triple helical chain structure with double cross linking.
- Functions as a potent agonist of the Glycoprotein VI (GPVI) receptor.
- Demonstrates high potency for both platelet activation and aggregation.
- Exceptional purity exceeding 99%.
- Consistently reliable from batch to batch.
Lyophilized CRP-A™ 0.5mg in glass vial. 10.118g/mol (10kDa).
- Recommended reconstitution: 1.0-2.5mg/ml.
- Compatible with the following solvents: water, saline solution or acetic acid (0.01M).
- Can be utilized in a variety of platelet aggregation applications involving platelet-rich plasma (PRP), and other platelet-derived therapeutic approaches.
- While using light transmission aggregometry (LTA) and p-selectin expression, the minimum dose that causes maximum aggregation is between 0.08-0.14µg/mL; and the minimum dose that causes maximum activation is between 0.22 µg/mL -0.30 µg/mL.
- CRP-A™ activity is in the range of concentration from 0.03 µg/mL to 10 µg/mL.
- Maintains consistent activation and growth factor release profiles.