Posted: June 25, 2019
David L. McGlasson, MS, MLS(ASCP) Posted: June 25, 2019 On May 9-11, 2019 the Hemostasis Thrombosis Research Society (HTRS) and North American Foundation of Thrombosis and Hemostasis (NAFTH) met in New Orleans, LA for a large Clotting and Bleeding Clam Bake of clinical and research information sharing. The first large exchange of information was that…
Posted: April 30, 2019
Factor XIII Quick Facts Molecular mass: 320 000 D Synthesis: Liver, Megakaryocytes Plasma concentration: 2mg/l Half-life: 8 days Normal range: 50 – 150% or 0.5 – 1.5U/ml Factor XIII, also known as fibrin stabilizing factor, is a heterodimer (FXIII-A2B2) composed of two catalytic A-subunits and two carrier B-subunits. With thrombin cleavage of the A-subunit followed by dissociation of the…
Posted: April 30, 2019
David L. McGlasson, MS, MLS(ASCP) Posted: April 30, 2019 As a follow-up to our Heparin issue, we bring you some stories of heparin in the news. “In the early 1980’s I was working at the University of Texas Health Science Center and University Hospital in San Antonio, TX. I was working in the Hemostasis Lab at…
Posted: March 25, 2019
David L. McGlasson, MS, MLS(ASCP) Posted: March 22, 2019 Since its introduction in 1953, the activated partial thromboplastin time (aPTT) has been used to monitor the treatment effect that heparin is having on a sample of blood. And for about as long, a litany of factors that interfere with the aPTT test’s ability to accurately measure…
Posted: February 26, 2019
David L. McGlasson, MS. MLS(ASCP)cm was a GS-13 staff researcher at the 59th Clinical Research Division at Lackland JBSA in San Antonio, TX until retirement.. He holds degrees from the University of Incarnate Word and San Antonio College in San Antonio, TX and certification from the Gradwohl School of Laboratory Technique in Medical Technology. In…
Posted: February 7, 2019
David L. McGlasson, MS, MLS(ASCP) THE FOLLOWING MEDICATION(s) MAY AFFECT THE COAGULATION OF YOUR BLOOD Vitamin E-, Ginseng, Garlic, Gingko Biloba, Feverfew, Fish Oil, Glucosamine. Celebrex, Vioxx, Aspirin (ASA, Baby ASA, CAMA, Ecotrin, Fiorinal) Percodan, Dislacid, ECASA, Zorprin Arthropan (Cholin salicylate); Voltaren (Diclofenac, Cataflam), Dolobid (Dilflunisal); Lodine (Etodolac); Nalfon (Fenoprofen Calcium) Ibuprofen- Advil,…
Posted: January 28, 2019
“HERE THE CLOT THICKENS” David L. McGlasson, MS MLS(ASCP) Welcome to Clot Club. Where are “a watched clot never thickens.” I am honored to be asked to start this hopefully long set of discussions on the mysteries and truths in the area of blood coagulation testing, theory and facts. Some people say “coag” is an…