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Faq: Can Chromogenix Coamatic® Antithrombin be used to measure mouse plasma?

Faq: Can I freeze the reagents in the Chromogenix Coatest® APC Resistance kits to prolong their stability?

Faq: Can I use Chromogenix Coatest® APC Resistance V without the predilution with FV deficient plasma? Isn't this just like using the APC R kit?

Faq: Can I use cryoprecipitate samples with the Chromogenix Coatest® FVIII kits?

Faq: Chromogenix Chromogenic substrate molecules images

Faq: Chromogenix Coamatic® Heparin is optimized for use with and without exogenous antithrombin. When is it recommended to add exogenous AT, and why?

Faq: Compare hirudin with heparin. How can hirudin level be determined?

Faq: Define a katal.

Faq: Define an enzyme and a substrate.

Faq: Describe chromogenic substrates in practice

Faq: Describe the measurement principle behind the discontinued Chromogenix Coamatic® Plasmin Inhibitor kit.

Faq: Does the Chromogenix Coatest® SP FVIII detect animal plasma?

Faq: Even though there is documentation that the anti-FXa method is better, how could a researcher determine antithrombin in plasma based on a thrombin method?

Faq: How do factor V and VIII levels affect the Chromogenix Coatest® APC Resistance tests?

Faq: How long has Diapharma been in business?

Faq: How should I make my standard pre-dilutions? It is not very clear from the Chromogenix Coamatic® Antithrombin package insert.

Faq: I need an assay that complies with the USP monograph for the determination of heparin activity. What test kits are suitable?

Faq: If I want to determine FX in plasma, but do not want to buy a kit, what other options are there?

Faq: If thrombin is formed, will it hydrolyze the substrate S-2765™ when using Chromogenix Coamatic®, Coatest® SP, or Coatest® SP4 FVIII kits?

Faq: In the Chromogenix Coamatic® Protein C assay, what substances could interfere with the assay, how will they affect results, and what can be done to overcome the interference?

Faq: In the Chromogenix Coatest® Heparin package insert, the section Limitations of the procedure states that in some pathological states, plasma alone my hydrolyze S-2222™, and that to determine the interference one should substitute FXa with an equal volume of buffer...Why is this necessary?

Faq: Is it OK to use glass tubes for the Chromogenix Factor VIII assay?

Faq: Sometimes when I run the Chromogenix Coamatic® FVIII assay, I see an upward drift in my activity from the first to the last samples. Why is this?

Faq: Substrate kinetic and selectivity tables

Faq: The activity of plasmin and plasminogen is expressed in CU. What is this, and what is the equivalent in nkat?

Faq: The Chromogenix Factor Xa reagent says it is 71 nkat, but I need to know what that is in g/ml and mol/ml.

Faq: The dilution of the 0.1 IU/ml heparin solution in Chromogenix Coatest® Heparin can cause some confusion. Please explain the Coatest® Heparin standardization.

Faq: The majority of the Chromogenix substrate library has an Arginine (Arg or R) group at the P1 position (the amino acid position that occurs at the preferred cleavage site). Why is this?

Faq: There are a few different substrates that are hydrolyzed by plasmin. If I want to use as short incubation times as possible, and need a selective substrate for plasmin, which should I choose?

Faq: We know that low levels of factor VIII activity constitutes hemophilia A, but are there any clinical manifestations of elevated factor VIII levels? How can a researcher measure elevated FVIII levels?

Faq: What aspects must a scientist consider when choosing the best chromogenic substrate?

Faq: What is a chromogenic substrate composed of?

Faq: What is a chromogenic substrate?

Faq: What is enzyme specificity and substrate selectivity?

Faq: What is the 53 nkat vial of thrombin equivalent to in NIH units?

Faq: What is the advantage of using the Chromogenix Coamatic® FVIII over a clotting test?

Faq: What is the Chromogenix Coamatic® Antithrombin measurement principle?

Faq: What is the Chromogenix Coamatic® Factor VIII measurement principle?

Faq: What is the Chromogenix Coamatic® Heparin measurement principle?

Faq: What is the Chromogenix Coamatic® LR Antithrombin measurement principle?

Faq: What is the Chromogenix Coamatic® Protein C measurement principle?

Faq: What is the Chromogenix Coatest® Heparin measurement principle?

Faq: What is the difference between Chromogenix Coamatic® FVIII, Coatest® SP FVIII, and Coatest® SP FVIII?

Faq: What is the difference between Chromogenix Coamatic® Heparin, Coatest® Heparin and the discontinued Coatest® Low Molecular Weight Heparin / Heparin?

Faq: What is the difference between Glu-plasminogen and Lys-plasminogen? How can the two forms be measured?

Faq: What is the measurement principle behind the FVIII chromogenic kits?

Faq: What substrate research methods are available?

Faq: What was the measurement principle behind the discontinued Coamatic® Plasminogen?

Faq: When exogenous AT is desired, how should it be added in the Chromogenix Coamatic® Heparin test?

Faq: Which assay should I run Chromogenix Coatest® APC Resistance or Coatest® APC Resistance V?

Faq: Which substrate is best suited for measuring two-chain tPA, and why?

Faq: Why did Chromogenix discontinue Coatest® Antithrombin and replace it with Coamatic® Antithrombin?

Faq: Why is pNA the leaving group on all of the Chromogenix substrates?

Faq: Why is thrombin added in the Chromogenix Coamatic® FVIII factor reagent?

Faq: Will elevated levels of plasminogen interfere with the Chromogenix Coamatic® Plasmin Inhibitor test?