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MASLD/MASH

 

Watch the Webinar: CK18 – the Key to Unlocking Informed Decisions in MASH Drug Trials

Are the Arrows Pointing in the Right Direction? CK18 Biomarkers Can Provide Insight into Your MASH Drug Candidate’s Future Success

The aims of this talk are to:

  1. Introduce the audience to the growing epidemic of MASLD
  2. Elucidate challenges in developing therapies for the treatment of MASH
  3. Provide an overview of CK18 and its role in MASH pathogenesis
  4. Present data that support the value of CK18 as a biomarker for assessing the efficacy of drugs in MASH clinical trials.


MASLD is characterized by an accumulation of fat in the liver, termed steatosis. Metabolic dysfunction associated steatohepatitis (MASH) occurs when steatosis progresses, causing inflammation and liver tissue injury, which can lead to hepatocyte death, fibrosis, inflammation, and scarring (cirrhosis). MASLD is the most prevalent chronic liver disease in the United States.

DiaPharma offers a diverse portfolio of ELISA assays for measuring blood-based biomarkers in liver research studies. Utilization of these biomarkers provides a non-invasive and accessible testing option to assess liver function and evaluate MASLD and MASH disease mechanisms. These biomarkers are currently being investigated to further understand the pathogenesis of MASLD and MASH liver diseases and to evaluate response to treatment in clinical trial and research settings.

Proteinase 3 (PR3)

Product Method / Application Packaging Species Use ? Catalog #

ImmunoDiagnostics Human Proteinase 3 (PR3) ELISA kit

ELISA Kit/96 tests Human RUO 31300

Leptin

Product Method / Application Packaging Species Use ? Catalog #

TECO® Leptin ELISA

ELISA Kit/96 tests Human RUO TE1016

WNT3A

Product Method / Application Packaging Species Use ? Catalog #

FluoBolt™ Wnt3A Protein Immunoassay

MEF-FIA (ELISA) 96 tests/kit Human RUO FIA-1705

Asporin

Product Method / Application Packaging Species Use ? Catalog #

FluoBolt™ Asporin

MEF-FIA (ELISA) Kit/96 tests Human RUO FIA-1702

Periostin

Product Method / Application Packaging Species Use ? Catalog #

FluoBolt™ Periostin

MEF-FIA (ELISA) Kit/96 tests - RUO FIA-1703

Hyaluronic Acid (HA)

Product Method / Application Packaging Species Use ? Catalog #

TECO® Hyaluronic Acid (HA) PLUS ELISA

ELISA Kit/96 tests Human RUO TE1018-2

Soluble CD163 (sCD163)

Product Method / Application Packaging Species Use ? Catalog #

IQ Macro163™ ELISA

ELISA Kit/96 tests Human RUO IQP-383

Mac-2 Binding Protein (M2BP)/Galectin-3 Binding Protein

Product Method / Application Packaging Species Use ? Catalog #

Mac-2 Binding Protein, Human

ELISA Kit/96 tests Human RUO DPG27362

Galectin-3

Product Method / Application Packaging Species Use ? Catalog #

ImmunoDiagnostics Human Galectin-3 ELISA kit

ELISA Kit/96 tests Human RUO 31690

Noggin

Product Method / Application Packaging Species Use ? Catalog #

FluoBolt™ Noggin

MEF-FIA (ELISA) Kit/96 tests Human RUO FIA-1701