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ADAMTS-13

ADAMTS13 , ADMATS-13 assay kitsADAMTS-13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) is an enzyme (vWF-cleaving protease or vWF-CP) that specifically cleaves von Willebrand Factor (vWF) multimers, a large protein involved in blood clotting. It is secreted in blood and degrades large vWF multimers. If the activity of ADAMTS-13 is decreased, unusually large vWF multimers may accumulate within blood causing thrombosis due to platelet aggregation, which in turn may lead to TTP (thrombotic thrombocytopenic purpura). Differentiation of TTP from other thrombotic microangiopathies (TMA) is challenging. Read more…

Product Method / Application Packaging Use ? Catalog #

Technozym® ADAMTS-13 Activity

ELISA Kit/96 tests RUO 5450701

Technozym® ADAMTS-13 Activity Calibrator

ELISA Box/6x0.5ml RUO 5450761

Technozym® ADAMTS-13 Activity Control

ELISA Box/2x0.5ml RUO 5450763

Technozym® ADAMTS-13 Activity Reaction Buffer

ELISA Box/30ml RUO 5450720

Technozym® ADAMTS-13 Activity Wash Buffer

ELISA Box/53ml RUO 5450750

Technozym® ADAMTS-13 Inhibitor

ELISA Kit/96 tests RUO 5450401

Technozym® ADAMTS-13 Inhibitor

ELISA Kit/48 tests RUO 5450451

Technozym® ADAMTS-13 Inhibitor Calibrator

ELISA Box/5x0.5ml RUO 5450461

Technozym® ADAMTS-13 Inhibitor Control

ELISA Box/2x0.5ml RUO 5450463

Technozym® ADAMTS-13 Antigen

ELISA Kit/96 tests RUO 5450601

Technozym® ADAMTS-13 Antigen Calibrator

ELISA Box/5x0.5ml RUO 5450661

Technozym® ADAMTS-13 Antigen Control

ELISA Box/5x0.5ml RUO 5450663

Technozym® ADAMTS-13 Fluorogenic Activity/Antigen

ELISA Kit/96 tests RUO 5450501

Technozym® ADAMTS-13 Fluorogenic Activity/Antigen

ELISA Kit/48 tests RUO 5450551

Technozym® ADAMTS-13 Calibrator

ELISA Box/5x0.5ml RUO 5450561

Technozym® ADAMTS-13 Control

ELISA Box/5x0.5ml RUO 5450563

Technoclone ADAMTS-13 Antibody Conjugate

Antibody Box/1ml RUO 5450555

Technoscreen® ADAMTS-13 Activity

Flow-Through Kit/10 tests RUO 5700100

Antithrombin

Antithrombin (AT) or Heparin Cofactor I is the major inhibitor of blood coagulation and is essential for effective heparin therapy. By inhibiting the coagulation proteases, especially thrombin, FXa and FIXa, AT prevents uncontrolled coagulation and thrombosis. Antithrombin deficiency is associated with a high risk of thromboembolic disorders. Read more…

Product Method / Application Packaging Use ? Catalog #

Technochrom® AT III Kit

Chromogenic Kit/100T RUO 5340224

Technochrom® AT III Manual Method Kit

Chromogenic Kit/39T RUO 5340225

Chromogenix Coamatic® Antithrombin

Chromogenic Kit/200 tests IVD K821991

Chromogenix Coamatic® LR Antithrombin

Chromogenic Kit/450 tests IVD K822957

APC Resistance (Factor V Leiden)

Activated Protein C (APC) is a regulator of the coagulation cascade, by specifically inactivating factors Va and VIIIa, in the presence of phospholipids and calcium.

Activated Protein C Resistance is tested by using a clotting method performed with or without Activated Protein C. Read more…

Product Method / Application Packaging Use ? Catalog #

Chromogenix Coatest® APC™ Resistance – V

Clotting Kit/80-160 tests IVD K823120

Chromogenix Coatest® APC™ Resistance – VS

Clotting Kit/40-80 tests IVD K823138

Chromogenix Coatest® APC™ Resistance

Clotting Kit/80-160 tests IVD K822643

Chromogenix Coatest® APC™ Resistance Control Plasma Level 1

Clotting Box/5x1ml IVD C822650

Chromogenix Coatest® APC™ Resistance Control Plasma Level 2

Clotting Box/5x1ml IVD C822668

C1-Esterase Inhibitor (C1-INH)

The C1-esterase inhibitor (C1-INH) is a regulatory protein that functions as an inhibitor of several serine proteases in the complement system, the kallikrein-kinin system, the coagulation cascade and in fibrinolysis.

Product Method / Application Packaging Use ? Catalog #

Technochrom® C1-INH

Chromogenic Kit/30 tests RUO 5345003

Ceveron Technochrom® C1-INH

Chromogenic Kit/60 tests (Ceveron) RUO 5345005

Direct Thrombin Inhibitors (DTI)

Product Method / Application Packaging Use ? Catalog #

Technoclot® DTI (Direct Thrombin Inhibitors)

Clotting Kit/2x20 tests RUO 5100025

Factor X (FX)

Coagulation Factor X (Stuart Prower Factor, FX) is a vitamin K dependent protein produced by the liver. It has a central position in the coagulation cascade. Factor X is activated both by the extrinsic and intrinsic systems before exerting its effect on the conversion of prothrombin to thrombin. Read more…

Product Method / Application Packaging Use ? Catalog #

Diapharma Factor X

Chromogenic Kit/200-400 tests IVD KDPGFX

Factor XIa (FXIa)

Factor XI (plasma thromboplastin antecedent) is a serine protease activated into factor XIa by factor XIIa (FXIIa), thrombin, and FXIa itself. FXI is a member of the coagulation “contact pathway” (which includes HMWK, prekallikrein, factor XII, factor XI, and factor IX). Read more…

Product Method / Application Packaging Use ? Catalog #

Rox Factor XIa

Chromogenic Kit/2x50 tests RUO 110050

Rossix FXIa Control

Chromogenic Box/10vials RUO 1188

Rossix FXIa Calibrator

Chromogenic Box/10vials RUO 1199

Factor XIII (FXIII)

Hemophilia ELISA Assay Test Kit Biomarker Factor XIII FXIII

Factor XIII (also know as fibrin stabilizing factor or Laki-Lorand factor) is an enzyme of the blood coagulation system that crosslinks fibrin. When thrombin has converted fibrinogen to fibrin, fibrin forms a proteinaceous network in which every E-unit is crosslinked to only one D-unit. Factor XIII is activated by thrombin into factor XIIIa; its activation into Factor XIIIa requires calcium as a cofactor. Read more…

Product Method / Application Packaging Use ? Catalog #

Technochrom® FXIII Kit

Chromogenic Kit/3x3ml RUO 5360010

Fibronectin

Product Method / Application Packaging Use ? Catalog #

Technozym® Fibronectin

ELISA Kit/96 tests RUO TC12030

Heparin

Heparin is an anticoagulant that prevents the blood clots. Heparin does not break down clots that have already formed (unlike tissue plasminogen activator) but allows fibrinolysis to work normally to break down clots.

Diapharma’s heparin kits are for the chromogenic determination of UF and LMW heparin in human plasma, and measure the ability of heparin to catalyze the inhibition of FXa by antithrombinRead more…

Product Method / Application Packaging Use ? Catalog #

Chromogenix Coamatic® Heparin

Chromogenic Kit/200 tests IVD K823393

Chromogenix Coatest® Heparin

Chromogenic Kit/400 tests IVD K255539

Protein C

Protein C is a vitamin K dependent plasma protein which plays an important role in the anticoagulant regulatory mechanisms. It circulates as a zymogen and is converted to an active serine protease, activated Protein C (APC), by the action of thrombin in presence of thrombomodulin. APC regulates the coagulation system by proteolytic cleavage and inactivation of activated factors V and VIII. Hereditary and/or acquired Protein C deficiency has been shown to be a risk factor for development of venous thrombosis. Read more…

Product Method / Application Packaging Use ? Catalog #

Chromogenix Coamatic® Protein C

Chromogenic Kit/288 tests IVD K822098

Technozym® Protein C INH Actibind®

ELISA Kit/96 tests RUO TC16100

Technozym® Protein C

ELISA Kit/96 tests RUO TC12021

REAADS Protein C Antigen

ELISA Kit/96 tests IVD K035-001

Technoclone Protein C Buffer, 20ml

Vial/20ml RUO 5341050

Technochrom® Protein C (for Ceveron® alpha)

Chromogenic Kit/30tests RUO 5341013

Technoclone Protein C Buffer, 60ml

Vial/60ml RUO 5341052

Protein S

Protein S (S-Protein) is a vitamin K-dependent plasma glycoprotein synthesized in the endothelium. Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding protein (C4BP).

Free Protein S plays a role in the anti-coagulation pathway, where it functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa. Read more…

Product Method / Application Packaging Use ? Catalog #

REAADS Monoclonal Free Protein S

ELISA Kit/96 tests IVD K051-001

REAADS Protein S Antigen

ELISA Kit/96 tests IVD K036-001

Prothrombin

Product Method / Application Packaging Use ? Catalog #

Rox Prothrombin

Chromogenic Kit/4x25 tests RUO 200040

Thrombin Generation

Product Method / Application Packaging Use ? Catalog #

Technothrombin® Thrombin Generation Assay (TGA)

Fluorogenic Kit/3x16 tests RUO 5006010

Technothrombin® Thrombin Generation Assay (TGA) Substrate (SUB), 5 x 1.5ml

Fluorogenic Box/5x1.5ml RUO 5006235

Technothrombin® Thrombin Generation Assay (TGA) Substrate (SUB), 50 x 1.5ml

Fluorogenic Box/50x1.5ml RUO 5006230

Technothrombin® Thrombin Generation Assay (TGA) Calibrator Set

Fluorogenic Box/1 set RUO 5006345

Technothrombin® Thrombin Generation Assay (TGA) Buffer (BUF)

Fluorogenic Box/5x3ml RUO 5006360

Technothrombin® Thrombin Generation Assay (TGA) Reagent A (RA), 5 x 0.5ml

Fluorogenic Box/5x0.5ml RUO 5006205

Technothrombin® Thrombin Generation Assay (TGA) Reagent A (RA), 50 x 0.5ml

Fluorogenic Box/50x0.5ml RUO 5006206

Technothrombin® Thrombin Generation Assay (TGA) Reagent B (RB), 5 x 0.5ml

Fluorogenic Box/5x0.5ml RUO 5006209

Technothrombin® Thrombin Generation Assay (TGA) Reagent B (RB), 50 x 0.5ml

Fluorogenic Box/50x0.5ml RUO 5006210

Technothrombin® Thrombin Generation Assay (TGA) Reagent C (RC) High, 5 x 0.5ml

Fluorogenic Box/5x0.5ml RUO 5006214

Technothrombin® Thrombin Generation Assay (TGA) Reagent C (RC) High, 50 x 0.5ml

Fluorogenic Box/50x0.5ml RUO 5006216

Technothrombin® Thrombin Generation Assay (TGA) Reagent C (RC) Low, 5 x 0.5ml

Fluorogenic Box/5x0.5ml RUO 5006212

Technothrombin® Thrombin Generation Assay (TGA) Reagent C (RC) Low, 50 x 0.5ml

Fluorogenic Box/50x0.5ml RUO 5006213

Technothrombin® Thrombin Generation Assay (TGA) Reagent D (RD), 5 x 0.5ml

Fluorogenic Box/5x0.5ml RUO 5006220

Technothrombin® Thrombin Generation Assay (TGA) Reagent D (RD), 50 x 0.5ml

Fluorogenic Box/50x0.5ml RUO 5006222

Technothrombin® Thrombin Generation Assay (TGA) Control High

Fluorogenic Box/5x1ml RUO 5006320

Technothrombin® Thrombin Generation Assay (TGA) Control – Low

Fluorogenic Box/5x1ml RUO 5006330

Ceveron® Thrombin Generation Assay (TGA) Reaction Buffer

Fluorogenic Box/5x1ml (Ceveron) RUO 5006370

Ceveron® Thrombin Generation Assay (TGA) Reaction Buffer

Fluorogenic Box/50x1ml RUO 5006372

Ceveron® TGA Substrate

Fluorogenic Box/5x3ml RUO 5006237

Ceveron® TGA

Fluorogenic Kit/3x60 tests RUO 5006012

Ceveron® TGA Reagent B

Fluorogenic Box/5x1ml RUO 5006202

Ceveron® TGA Reagent C High

Fluorogenic Box/5x1ml (Ceveron) RUO 5006227

Ceveron® TGA Reagent B

Fluorogenic Box/50x1ml RUO 5006204

Ceveron® TGA Reagent C High

Fluorogenic Box/50x1ml RUO 5006228

Ceveron® TGA Reagent C Low

Fluorogenic Box/5x1ml (Ceveron) RUO 5006224

Ceveron® TGA Reagent C Low

Fluorogenic Box/50x1ml (Ceveron) RUO 5006225

Ceveron® TGA RC Low Kit

Fluorogenic Kit/2x60 tests RUO 5006013

Ceveron® TGA Calibrator Set

Fluorogenic Box/1 set RUO 5006347

Ceveron® TGA Control Low

Fluorogenic Box/5x1ml RUO 5006332

Ceveron® TGA RB Kit

Fluorogenic Kit/2x60 tests RUO 5006011

Ceveron® TGA Control High

Fluorogenic Box/5x1ml RUO 5006322

Ceveron® TGA RC High Kit

Fluorogenic Kit/2x60 tests RUO 5006015

Technothrombin® Thrombin Generation Assay (TGA) MFC

Box/5x1ml RUO 5006351

Technothrombin® Thrombin Generation Assay (TGA) MHC

Box/5x1ml RUO 5006352

Technothrombin® MP

Kit/3x16 tests RUO 5006400