DISCONTINUED – REPLACEMENT: MP0250
Multiplate® TRAPtest is a reagent kit used for platelet aggregation research studies for the evaluation of normal platelet function on the Multiplate® Analyzer and for the research evaluation of qualitative platelet function inhibition. Sensitive to the action of glycoprotein (Gp) IIb/IIIa receptor antagonists and/or a deficiency of GpIIb/IIIa receptors.
Reagents, Storage and Stability
- MP0195: Multiplate® TRAPtest reagent, Kit, 1 x 1.0 mL. 50 tests. Reagent is stable until the expiration date printed on the vial label when stored at 2-8°C. Stable 7 days after reconstitution when stored at 2-8°C. Stable 4 weeks after reconstitution when stored at < -20°C. Stable for 24 hours at room temperature after one time thawing.
In the TRAPtest, platelets are activated by TRAP-6, a peptide that mimics the activation of platelets by the action of thrombin. Thrombin is the most potent platelet activator. The action of thrombin is not blocked by the antiplatelet agents Aspirin® or clopidogrel. However, thrombin (and TRAP-6) activated platelets are blocked by the action of GPIIb/IIIa antagonists (e.g., ReoPro®, Aggrastat® and Integrilin®).