Haematex DOAC test is RVV-based ready for use reagent with high sensitivity to all new direct oral anticoagulants (DOACs). New or novel oral anticoagulants (NOACs / DOACs) include direct inhibitors of thrombin (e.g. argatroban and dabigatran) as well as factor Xa (e.g. rivaroxaban, apixaban and edoxaban). The latter are difficult to quantitate using current clotting methods and chromogenic assays for individual DOACs have been developed. DOAC test reagent is a modified phospholipid-rich dilute Russell’s viper venom reagent with enhanced sensitivity to the new oral anti-coagulants. The reagent is ready for use and stable for approximately 1 year stored at 4°C.