Finally – A New Option to Measure Human Wnt3A Protein
Posted: April 21, 2021
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Detect the Undetectable
Light up your Wnt3A
Lack of commercial and high-throughput options to measure Human Wnt proteins in serum has hampered Wnt-signaling research for too long. A new immunoassay technology, FluoBolt™, now offers the Wnt-signaling community an easier and more robust measurement of Wnt3A. This expands research options for studying mechanisms of disease and use of Wnt3A as a biomarker in clinical research.
FluoBolt™ Wnt3A kit benefits:
- Super simple and fast protocol
- Robust fluorescent signal output
- Open platform technology (most standard plate readers)
- 96 well format
- Ready-made standards and controls
- Serum-based matrix
- Multiple fluorophore label options available
- Focus on quality from Austrian-based manufacturer, Fianostics
Kits are available for purchase via DiaPharma in the US and Canada OR send your samples to Fianostics for FluoBolt™ analysis services.
FluoBolt™ Methodology:
Nano-structured metal enhances signal from fluorophores conjugated to detection antibodies close to bottom of the plate. This produces a more robust signal than standard ELISA methods and reduces background signal.
Available FluoBolt™ kits:
- FluoBolt™ Noggin
- FluoBolt™ Asporin
- FluoBolt™ Periostin
- FluoBolt™ Wnt3a
- FluoBolt™ alpha-Klotho
| Amino Acid Sequence Identity with Human | |||||||
| Source | https://www.uniprot.org | ||||||
| Mouse | Rat | NHP | Pig | Canine | Zebra Fish | Hamster | |
| Periostin | 90% | 87% | 92-93% | 95% | 96% | 54% | 89% |
| Asporin | 89% | 89% | 96-99% | 89% | 89% | 54% | 89% |
| Noggin | 99% | 99% | 99-100% | 99% | 96% | 55% | 99% |
| Wnt3a | 96% | 89% | 99-100% | 96% | 71% | 82% | 96% |
| Klotho | 86% | 84% | 93-99% | 88% | n.a. | 50% | 85% |
Research Use Only in U.S. and Canada. Not for use in diagnostic procedures.
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