Thrombin Generation Assays

Posted: April 4, 2019

 

Technothrombin
TGA
Ceveron
TGA
Calibrated Automated ThrombogramThrombodynamics
4D
Hands-On Time30 minutes<5 minutes30 minutes<5 minutes
Assay Time60 minutes40 minutes60 minutes60 minutes
Complexity to OperateStandard Laboratory Skills and EquipmentBasic Laboratory Skills and EquipmentStandard Laboratory Skills and EquipmentSingle-Button Operation
BarcodeNoYesNoYes
Plasma Volume40 µL/Reaction40 µL/Reaction80 µL/Reaction120 µL/Reaction
Calibration RequiredYes, curveYes, curveYes, curveNo
Individual α2M Calibrator Not NeededNot NeededNecessary for Every SampleNot Needed
Total Volume100 µL150 µL120 µL125 µL
Assay Format96 Well PlateCuvette96 Well Plate2 Channel Cuvette
Throughput~48 Samples/Hour~48 Samples/Hour~48 Samples/Hour2 Samples/Hour
AnalysisExcel ApplicationCeveron AlphaThrombinoscopeThrombodynamics
ReactionHomogenousHomogenousHomogenousPropagation from surface
TriggerVariableVariableVariableVariable
Thrombin Generation ParametersLag Time (min)Lag Time (min)Lag Time (min)Lag Time (min)
Peak Thrombin (nM)Peak Thrombin (nM)Peak Thrombin (nM)Peak Thrombin (AU/L)
Velocity IndexVelocity IndexTime to Peak (min)Time to Peak (min)
Total Thrombin
Potential
Total Thrombin
Potential
Endogenous Thrombin PotentialTotal Thrombin Potential (AU*min/L)
Rate of Thrombin Propagation (µm/min)
Amplitude of Stationary Thrombin Peak (AU/L)
Additional ParametersClotting AssaysSpatioTemporal Dyanmics of Fibrin Propagation
 Chromogenic AssaysClot Size (µm)
 Turbidimetric AssaysClot Density (a.u.)

 


TGA COMPARISON


Research use only in the US and Canada     800.526.5224     www.diapharma.com     info@diapharma.com

ML-00-00424REV01