Keratin 18: A Non-Invasive Biomarker for Organ Damage

Posted: August 4, 2020

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The quality you trust from Diapharma for SARS-CoV-2 Research

SARS-CoV-2 ELISA COVID-19 research

Keratin 18 (K18/CK18)

A non-invasive biomarker for multi-organ damage

  • Assess cell death associated with multi-organ failure due to COVID-19 related sepsis and tissue damage
    • Measure circulating K18: K18 is expressed in cells of epithelial origin, including lung, GI, kidney, and liver
  • M65® ELISA: Measures total cell death (necrosis + apoptosis)
  • M30® Apoptosense: Specific for apoptosis

Research use only in the U.S. and Canada. Not for use in diagnostic procedures.

Visit diapharma.com for a complete list of mechanistic biomarkers for COVID-19 research, including our SARS-CoV-2 ELISAs, ideal for COVID-19 research, epidemiological studies, and vaccine development.

keratin 18

Beware of Imposters!

Not all K18 kits are created equal.

  • The M30® Antibody is a unique antibody that detects a caspase-cleaved epitope of K18
  • Look for the trademark on the M30® & M65® kits
  • Only available through Diapharma in the U.S. and Canada
  • The M30 Apoptosense® kit was optimized to allow for better discrimination between normal and abnormal samples (Bantel H et al 2014).

keratin 18

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