Describe the measurement principle behind the discontinued Chromogenix Coamatic® Plasmin Inhibitor kit.

Incubation of diluted plasma with an excess of plasmin results in a rapid complex formation between functional plasmin inhibitor present in the plasma and plasmin. The inhibited plasmin activity is proportional to the amount of plasmin inhibitor. The remaining amount of plasmin hydrolyzes the chromogenic substrate S-2403™, thus liberating the chromophoric group pNA.