Uncategorized

Complimentary Webinar: ATLAS PST: A New Dimension in Platelet Function

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Complimentary Webinar

ATLAS Platelet Strength Test: A New Dimension in Platelet Function

Wednesday, May 22 at 1 p.m. EDT

 

ATLAS PST instrument

The newest way to correlate platelet strength and size with functionality

DiaPharma is excited to invite you to a webinar where we will delve into the innovative ATLAS PST technology and its unparalleled functional measurements for platelet biomechanics on a multi-platelet scale. Discover how the ATLAS PST leverages machine learning alongside microscopy to unveil intricate insights into platelet aggregation, clot size, and contractile forces within whole blood samples. Moreover, join us as we explore the vast potential of artificial intelligence in identifying unique patterns of dysfunction associated with platelet-related diseases across various medical research domains such as trauma, personalized medicine, blood banking, and cancer-associated thrombosis.

Bring your questions and discover how the ATLAS PST can revolutionize your platelet research.

The ATLAS PST instrument and consumables are for research use only. Not for use in diagnostic procedures.

REGISTER DiaPharma CK18 MASH


As the sample moves through the analysis chamber, microclots form and the force of the bond is measured.

The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors in the blood to assess coagulopathy

Top: The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors in the blood to assess coagulopathy.

Bottom: As the sample moves through the analysis chamber, microclots form and the force of the bond is measured.


Stasys proprietary sensor technology - An individual sensor at the micron scale, and the shear gradients that it creates on passing streamlines of blood.

An individual sensor at the micron scale, and the shear gradients that it creates on passing streamlines of blood.


For research use only in the U.S. and Canada. Not for use in diagnostic procedures.


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Connect with a DiaPharma Scientist

DiaPharma olivia matt mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-10-00014Rev01

Clot Club #52

Clot Club #51

EXPLORING UNMET NEEDS IN ISLET CELL TRANSPLANTATION AND STEM CELL-DERIVED ISLET RESEARCH

Discover Technozym ADAMTS13 Activity for Your Clinical Laboratory

It’s Not Just Support. It’s Solutions.


ADAMTS13 Activity ELISA measurement test kit

TECHNOZYM ADAMTS13 ACTIVITY KIT

DiaPharma is pleased to offer the first in vitro diagnostic (IVD) test to receive marketing authorization by the FDA.

The Technozym ADAMTS13 Activity assay is an enzyme-linked immunosorbent assay (ELISA) intended for the qualitative determination of ADAMTS13 activity in platelet poor human citrated plasma. The assay is intended to be used in conjunction with other clinical and laboratory findings as an aid in the diagnosis of thrombotic thrombocytopenic purpura (TTP) in adult and pediatric patients being evaluated for thrombotic microangiopathy (TMA).

DiaPharma is proud to partner with Technoclone to lead the way for better access to this important test, addressing an unmet need for laboratories and patients across the U.S.

ADAMTS13 Activity ELISA Measurement Kit IVD

Technozym ADAMTS13 Activity Chromogenic ELISA features:

  • Calibrators and Controls are traceable to WHO 1st international Standard ADAMTS13 plasma
  • No interference by bilirubin, lipemic samples up to 500 mg/dL, or hemolytic samples up to 220 mg/dL
  • Straightforward ELISA format

ADAMTS13 Activity ELISA measurement test kit

LEARN MORE

diapharma

It’s Not Just Support. It’s Solutions.

View our full portfolio of hemostasis assays at diapharma.com or

connect with a DiaPharma scientist to learn more.

Diapharma Jen Mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01161Rev01

Complimentary Webinar: CK18 – the Key to Unlocking Informed Decisions in MASH Drug Trials

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

You’re Invited: Complimentary Webinar

CK18 – the Key to Unlocking Informed Decisions in MASH Drug Trials

Are the Arrows Pointing in the Right Direction? CK18 Biomarkers Can Provide Insight into Your MASH Drug Candidate’s Future Success

Tuesday, April 23 at 1 pm EDT

VLV Liver CK18 MASH

When: Tuesday, April 23 at 1 PM EDT

What: Metabolic-associated steatotic liver disease (MASLD, formerly known as NAFLD) is the most common form of chronic liver disease in developed countries. MASLD affects over 38% of the population worldwide and its prevalence is projected to grow to over 55% by the year 2040.

Individuals that have progressed to the more advanced form of this disease, metabolic dysfunction-associated steatohepatitis (MASH, formerly known as NASH), are at an increased risk for liver-related complications such as cirrhosis and hepatocellular carcinoma (HCC), as well as other serious health problems.

While the recent FDA accelerated approval of the first pharmacologic therapy for MASH, Rezdiffra® (resmetirom), marked a truly historic milestone, many more drugs with diverse mechanisms of action are currently in development – with new candidates entering into pipelines every day – to address this complex and etiologically diverse disease. Improvements in liver histology confirmed through biopsy continue to be required endpoints for regulatory approval, however, non-invasive biomarkers may be used in early-stage trials to assess treatment effects.

Serum Cytokeratin 18 (CK18), measured by the PEVIVA® M30® Apoptosense® and M65® ELISAs, is a biomarker that has been included as a secondary and exploratory endpoint in over 70 clinical trials of drug candidates that are targeting MASH. CK18 levels are reflective of hepatocyte apoptosis and necrosis, which are thought to be important processes involved in the progression of MASH. Monitoring serum CK18 levels, therefore, provides mechanistic information on the effect of drug treatment in MASH clinical trials. Furthermore, decreases in serum CK18 levels have been shown to be reflective and predictive of improvements in liver histology.

The aims of this talk are to:

  1. Introduce the audience to the growing epidemic of MASLD
  2. Elucidate challenges in developing therapies for the treatment of MASH
  3. Provide an overview of CK18 and its role in MASH pathogenesis
  4. Present data that support the value of CK18 as a biomarker for assessing the efficacy of drugs in MASH clinical trials.

 REGISTER DiaPharma CK18 MASH


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01154Rev01

Visit DiaPharma at AACR 2024

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Visit DiaPharma at AACR Booth 511

DiaPharma representatives will be at AACR in the Volition booth to talk about nucleosomes, epigenetic markers, and their utility in cancer research and drug development. Reach out to connect with Dr. Jessica Tuohy or Dr. Olivia Stricker!

Stop by to learn more about Volition’s Nu.Q® technology and the Discover H3.1 ELISA Research Use Only kit that detects quantitative levels of circulating intact nucleosomes containing Histone H3 in plasma. This kit is the first standardized, off-the-shelf, commercial option available for clinical research.

Connect with Jessica and Olivia DiaPharma

AACR 2024

For Research Use Only. Not for use in diagnostic procedures.

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01151Rev01

Connect with DiaPharma at THSNA

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

MEET US AT THSNA!

We would love to see old friends and meet new acquaintances at the Thrombosis & Hemostasis Summit of North America (THSNA), April 3 – 6 in Chicago.

Our scientists are eager to discuss the latest in Coagulation, Platelet Function Testing, NETs, ADAMTS13 Research, MMPs, and more.

We are also excited to offer the Technozym ADAMTS13 Activity ELISA, the first to be granted IVD medical device market authorization from the FDA!

We Deliver Solutions

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Talk with us about:

  • Do-it-all Coagulation Analyzers
  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Innovative solutions to profiling nucleosomes
  • Anticoagulation Measurement Kits and Reagents
  • Anti-Hemoglobin antibodies for Sickle Cell Disease research
  • Biomarkers for early detection of liver injury during AAV gene therapy trials

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01146Rev01

Explore the Atlas PST – a New Dimension of Platelet Analysis

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Balancing Platelet Strength & Function with the Stasys Atlas PST

Atlas PST detects all mechanisms of platelet dysfunction in less than 3 minutes.

  • Global assay of primary hemostatic potential
  • Whole blood specimen for rapid analysis (< 3 minutes)
  • Uniquely measures platelet contractile forces, aggregation, and function
  • Reagents and agonists not needed – easy to bring in-house
  • User-friendly device has small footprint (~1 sq ft)
  • Fully-automated workflow, reporting real-time data in minutes

LEARN MORE


As the sample moves through the analysis chamber, microclots form and the force of the bond is measured.

The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors in the blood to assess coagulopathy

Top: The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors in the blood to assess coagulopathy.

Bottom: As the sample moves through the analysis chamber, microclots form and the force of the bond is measured.


Add data in a multitude of research applications:

  • Research and drug development of potential therapeutics to restore primary hemostasis in e.g. ECMO subjects, anti-vWF agents, etc.
  • Bleeding risk / coagulopathy in trauma, sepsis, and DIC
  • Acute thrombosis (e.g. subjects with coronary artery disease before/after intervention, PAD, COVID, cancer-associated thrombosis)
  • Antiplatelet drug titration
  • Hereditary platelet disorders

For research use only in the U.S. and Canada. Not for use in diagnostic procedures.


Stasys proprietary sensor technology - An individual sensor at the micron scale, and the shear gradients that it creates on passing streamlines of blood.

An individual sensor at the micron scale, and the shear gradients that it creates on passing streamlines of blood.


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Connect with a DiaPharma Scientist

DiaPharma olivia matt mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-10-00011Rev01

Technoclone Receives US FDA Marketing Authorization for the First ADAMTS13 Activity Test

It’s Not Just Support. It’s Solutions.


DiaPharma Technoclone

Technozym ADAMTS13 Activity granted marketing authorization by the FDA

DiaPharma and Technoclone are pleased to announce the FDA De Novo classification grant and authorization to market the first in vitro diagnostic (IVD) assay for the qualitative determination of ADAMTS13 activity.

The Technozym ADAMTS13 Activity assay is an enzyme-linked immunosorbent assay (ELISA) intended for the qualitative determination of ADAMTS13 activity in platelet poor human citrated plasma. The assay is intended to be used in conjunction with other clinical and laboratory findings as an aid in the diagnosis of thrombotic thrombocytopenic purpura (TTP) in adult and pediatric patients being evaluated for thrombotic microangiopathy (TMA).

DiaPharma is proud to partner with Technoclone to lead the way for better access to this important test, addressing an unmet need for laboratories and patients across the U.S.

DiaPharma Press Release

ADAMTS13 Activity ELISA Measurement Kit IVD

We Deliver Solutions

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01140Rev01

Meet Your Diabetes Drug Development Needs with TECO Intact Proinsulin

It’s Not Just Support. It’s Solutions.

Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

How can blood-based biomarkers enrich your Type 1 Diabetes (T1D) study population?

 

TECO® Intact Proinsulin ELISA

When it comes to measuring pancreatic Beta cell function, go with the Pro! Save time and guess work by selectively measuring only intact proinsulin.

Intact Proinsulin is produced by beta-cells (β-cells) in the pancreas and it is enzymatically processed into insulin and C-peptide. It is an early indicator of β-cell stress associated with both type 1 and type 2 diabetes (T1D and T2D).

The TECO® Intact Proinsulin ELISA specifically measures intact proinsulin, providing a direct measure of pancreatic β-cell function.

Are you attending the 17th International Conference on Advanced Technologies & Treatments for Diabetes?

DiaPharma’s Dr. Abi Kasberg is heading to Florence to learn more about the utility of intact proinsulin as a biomarker in diabetes, about the future of therapeutics related to diabetes, and how the new drugs in the T1D space change the field. She looks forward to insightful conversation with scientists and physicians while indulging in Italy’s finest foods. Let us know if you’ll be there!

DiaPharma Abi Teco ProInsulin Insulin ELISA Measurement Assay

Benefits of the TECO® Intact Proinsulin ELISA:

  • Reliable tool for diabetes research and related drug development studies
  • Provides valuable information regarding defects in proinsulin processing as an early indicator of β-cell stress
  • Measures only intact proinsulin for a cleaner readout – total proinsulin assays measure intact proinsulin as well as des-proinsulin cleavage fragments.
    Standardized against WHO reference 09/296
  • Assay time less than 3 hours means fast results – no need for overnight incubation

Leading Expertise in Type 1 Diabetes Research Assays

For research use only in the U.S. and Canada. Not for use in diagnostic procedures.


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,

with support just a call or click away.

DiaPharma olivia matt mike

Visit diapharma.com ProInsulin Insulin Measurement ELISA Assay

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01137Rev01

Are your patients properly anticoagulated?

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Measuring Warfarin in Patients

with a Lupus Anticoagulant

Throughout last year, the use of DOACs in patients with antiphospholipid antibody syndrome (aPS) has been debated. Here we address two key questions:

  • What are the options for monitoring a patient with the presence of a strong LA inhibitor, where INRs might be unreliable?
  • What test can measure the effect of warfarin to help ensure the patient is in therapeutic range?

The chromogenic Factor X assay can be used here to measure % Factor X (FX) levels. Chromogenic FX activity levels have shown utility for monitoring warfarin therapy in patients where INR is unreliable, such as in aPS.

The DiaPharma Factor X Kit is accessible, FDA cleared, and offered by reference labs across the U.S.

Visit diapharma.com to learn more.

Factor X, chromogenic Factor X assay

Reference: Rosborough T.K., Shepherd M.F. Unreliability of international normalized ratio for monitoring warfarin therapy in patients with lupus anticoagulant. Pharmacotherapy. 2004;24(7):838–842.

View our full portfolio of hemostasis and thrombosis assays at diapharma.com.

 Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-01-00015Rev01

Complimentary Webinar – Nothing but NETs: Unraveling biomarkers for NETosis research

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

Register today for
Nothing but NETs: Unraveling biomarkers for NETosis research

A webinar aimed to examine widely used biomarkers of NETosis, and understanding how they can best used to paint a complete picture of relevant events in disease. This presentation hopes to highlight commonly used assays, while introducing Volition’s nucleosome detection tool, Nu.Q® Discover H3.1 ELISA Research Use Only Kit.

Join in the conversation and feel free to share what your go-to assay is for NET detection in clinical research samples.

Time: Jan 17, 2024 11:00 AM Eastern Time (US and Canada)

Agenda: 20 minutes of presentation and 5-10 minutes of questions/discussion

Presenter: Terry Kelly, Ph.D., Chief Innovation Officer, VolitionRx Limited

NETosis Nu.Q® Discover H3.1 ELISA

Nu.Q® Discover H3.1 ELISA Research Use Only Kit is for research use only. Not for use in diagnostic procedures.

Nu.Q® is a trademark of VolitionRx Limited and its subsidiaries.


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Find Your Territory Manager

DiaPharma olivia matt mike

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01128Rev01

DiaPharma is looking forward to NASH-TAG 2024

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

LOOKING FORWARD TO NASH-TAG 2024

There is no better way to start the year than getting immersed in the latest developments in the field of Metabolic Dysfunction-Associated Steatohepatitis (MASH)!

DiaPharma is attending the upcoming NASH-TAG 2024 conference January 4 – 6 in Deer Valley, UT. Every year, NASH-TAG delivers unparalleled insights into cutting-edge research and opportunities for provocative discussions with top experts.

We look forward to gaining fresh perspectives, seeing old friends, and meeting new acquaintances. See you in the sessions and on the slopes!

jes diapharma

If you’re also attending, we’d love to connect! Reach out to Jessica Tuohy, Ph.D. to schedule some time.

diapharma jessica

diapharma


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01127Rev01

Clot Club #50

DO WE NEED TO STANDARDIZE COAGULATION NOMENCLATURE IN TODAY’S LABORATORY ENVIRONMENT?

Connect with DiaPharma at ASH 2023

It’s Not Just Support. It’s Solutions.


Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13, MMPs, Nu.Q

MEET US AT ASH 2023

We would love to see old friends and meet new acquaintances at the ASH 2023 December 9 – 12 in San Diego.

Our scientists are eager to discuss the latest in Coagulation, Platelet Function Testing, NETs, Neutrophil Elastase Activity testing, ADAMTS13 Research, MMPs, and more!

Be sure to check out these posters from Volition, manufacturer of the Nu.Q® Discover H3.1 ELISA* Research Use Only Kit:

  • 3907: High-Throughput Screening to Develop a Biologically Relevant Netosis Induction Model, presented by Kieran Zukas
  • 2542: Understanding Netosis Priming and Induction through Nucleosome Changes and Real-Time Monitoring in Isolated Neutrophils and in an Ex-Vivo Model, presented by Andrew Retter.

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Talk with us about:

  • Innovative solutions to profiling nucleosomes
  • Neutrophil Elastase Assays
  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Anti-Hemoglobin antibodies for Sickle Cell Disease research
  • Biomarkers for early detection of liver injury during AAV gene therapy trials

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01124Rev01

Thank you for visiting DiaPharma at AASLD The Liver Meeting®

It’s Not Just Support. It’s Solutions.


 MASH, ALD, MetALD, DILI, CK18/K18 M30 Apoptosense, M65 ELISAs

THANK YOU FOR VISITING DIAPHARMA

AT AASLD THE LIVER MEETING®!

MASH, ALD, DILI, CK18 ELISA, NET, Nu.Q H3.1

We enjoyed speaking with you about MASH, ALD, MetALD, and DILI and the use of CK18/K18 M30® Apoptosense and M65® ELISAs as blood-based biomarkers for clinical research and drug trials at 2023 AASLD The Liver Meeting®.

Your Territory Manager will be reaching out to follow up on the specifics of the conversations we had and share more about the solutions we offer for your project.

Our team’s take aways from the meeting were mostly about the emphasis this year on Alcohol Associated Liver Disease (ALD) and microphysiological systems (MPS) for liver. We have watched the interest in both topics significantly grow over the years and are excited to have relevant solutions to offer in each area.

Learn more about our full portfolio of products for studying liver injury at diapharma.com.

For research use only in U.S. and Canada. Not for use in diagnostic procedures.

LEARN MORE

MASH, ALD, DILI, CK18 ELISA, NET, Nu.Q H3.1

diapharma


It’s Not Just Support. It’s Solutions.

Celebrating 25 years of scientific expertise, just a call or click away.

MASH, ALD, DILI, CK18 ELISA, NET, Nu.Q H3.1

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01114Rev01

Clot Club #49

OUT WITH THE FATTY LIVER… IN WITH THE NEW NOMENCLATURE

Thank you for connecting with DiaPharma at AABB 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Thank you for connecting with us at AABB

We enjoyed seeing old friends and meeting new acquaintances at the AABB 2023 meeting. We had the opportunity to discuss the all-in-one Ceveron® s100* with ADAMTS13 Activity* in less than 30 minutes, along with new technology in platelet function measurement, featuring the T-TAS® 01 PL Assay and Atlas PST*. We also had the pleasure of introducing the Nu.Q® Discover H3.1* Research Use Only ELISA, the innovative, ready-to-run reagent-complete kit for profiling nucleosomes. On the anticoagulation side, we were excited to discuss our FDA-cleared chromogenic DiaPharma Factor X for warfarin monitoring when INRs are unreliable, along with our selection of anti-Xa assays.

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

ceveron s100, adamts13, t-tas, nu.q h3.1, factor x, anti-xa

Our team will be reaching out to provide specific product information. We invite you to connect with a DiaPharma scientist with any questions as well.

Connect with a DiaPharma Scientist

DiaPharma provides:

  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Marker Assays
  • Thromboinflammation Marker Assays
  • NETosis Research Assays
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Biomarker assays for early detection of liver injury during AAV gene therapy trials

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01105Rev01

Clot Club #48

THE STANDARDIZATION OF NET MEASUREMENTS, A WORK IN PROGRESS

DiaPharma has a lot to share at The Liver Meeting® – come see us!

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

VISIT DIAPHARMA
AT THE LIVER MEETING®!

MASH, ALD, DILI, CK18 ELISA, NET, Nu.Q H3.1

We are looking forward to learning the latest expert insights about MASH, ALD, DILI, and introducing ourselves to metALD, at the 2023 AASLD The Liver Meeting®.

This is one of DiaPharma’s favorites for sharing information on our CK18/K18-M30® and CK18/K18-M65® ELISAs, blood-based biomarkers to measure liver injury of all types. CK18 is a hepatocyte death marker, used to understand disease activity, frequently used as a biomarker in a variety of drug development and drug trial scenarios. These non-invasive tests (NITs) are exploratory endpoints for early efficacy, and correlate with the ever-elusive ballooning cell.

Who is studying NETs related to liver? If you are, come and learn about Volition Nu.Q® Discover H3.1 Research Use Only ELISA, an innovative, ready-to-run complete solution to profiling nucleosomes.

Booth D3217 is where Team DiaPharma will be. We invite you to stop by and discuss these intriguing topics.

For research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Celebrating 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01108Rev01

DiaPharma now hiring QA / RA Manager


Quality Assurance & Regulatory Affairs Manager
DiaPharma Group, Inc. – West Chester, Ohio
Hybrid – three days per week onsite

DiaPharma Group specializes in laboratory assay kits, reagents, and instrumentation for research and clinical applications in the fields of coagulation, platelet function, bleeding and clotting disorders, cell death, liver injury, and oncology. We deliver solutions and support to our customers.

Our in vitro diagnostic test kits and instruments are used in hospital laboratories, clinical reference laboratories, universities, and pharmaceutical companies. Our line of research products is used by researchers and medical corporations for product development, clinical research studies, and in quality control laboratories.

We seek a seasoned Quality Assurance – Regulatory Affairs Manager to manage quality systems, processes, and procedures to assure product safety and quality.  This individual will drive business alignment to correct industry requirements by managing quality system design, controls, and continuous improvement.

Key responsibilities include:

  • Serve as Management Representative.
  • Promote audit readiness, prepare company for inspections by external bodies, including FDA, Health Canada, and customers, and facilitate audits and inspections.
  • Own and manage quality systems, processes, policies, and procedures to assure product quality and safety across the business.
  • Engage strong intradepartmental and cross-functional/organizational relationships to drive Quality System Requirements (QSRs).
  • Influence and track quality system metrics such as Corrective and Preventive Action, training metrics, and complaint resolution metrics.
  • Ensure compliance to FDA and Health Canada regulations.
  • Ensure/follow up/implement corrective actions that are raised by deviations, internal audit, or regulatory inspection.
  • Spearhead and prepare regulatory submissions and perform regulatory activities, such as 510(k) and de novo submissions.
  • Other duties as assigned.

 

Requirements include:

  • Bachelor’s degree or higher.
  • 3 to 5 years of experience working in the medical device industry, specifically in area of Quality Assurance and Regulatory Affairs.
  • Experience with in vitro diagnostics (IVDs) a plus.
  • Demonstrated knowledge of medical device quality system regulations (e.g. QSR, ISO 13485, MDSAP), including Design Control, DMRs/DHFs, CAPA, Complaints, Risk Management, Document Control, Training, Complaint Handling, and Audits.
  • Ability to interface with top organizational leadership and internal and external customers, responding in a professional manner.
  • Experience with the following:
    • Preparing FDA submissions, license applications, registrations and other product approval documentation.
    • Analytical & problem-solving skills/root-cause analysis.

We offer:

  • A competitive salary.
  • Generous PTO and paid holiday schedule.
  • Abbreviated Friday schedule.
  • Superior medical, dental, life, STD & LTD insurance.
  • 401(k) participation with generous match.
  • Supportive work environment.
  • Continuing education and training opportunities.

 

* Benefits may be subject to eligibility requirements and waiting period.

DiaPharma Group, Inc., provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

This employer participates in E-Verify.

 

For consideration, please forward your resume to employment@diapharma.com.

What’s New at DiaPharma? Ted Lasso said it best…

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Our Commitment to Be Curious

DiaPharma held our semiannual company-wide meeting this summer. On the work side, we channeled Ted Lasso in our commitment to be curious. We reaffirmed who we are: scientific support, solutions-based sales, accommodating customer service, and common-sense operations. One DiaPharma team, working together, to provide a helpful and personal experience so our customers accomplish their goals.

On the play side, we tried our hands at TopGolf and Pickleball, both of which were taken as seriously as our commitments in business. Congrats to Tom Boulden and Ryan McCaw, our Pickleball champs!

diapharma


Meet us in person at the following events:

  • Mayo Classical Hematology Conference: October 3 – 4 in Rochester, MN
  • Mayo Bleeding and Thrombosing Diseases Conference and Workshop: October 4 – 6 in Rochester, MN
  • Society for the Advancement of Patient Blood Management (SABM): October 4 – 7 in Nashville, TN
  • Association for the Advancement of Blood and Biotherapies (AABB): October 13 -17 in Nashville, TN
  • AASLD The Liver Meeting®: November 10 – 14 in Boston, MA
  • American College of Rheumatology (ACR) Convergence: November 10 – 15 in San Diego, CA
  • American Society of Hematology (ASH) Annual Meeting and Exposition: December 9 – 12 in San Diego, CA

DiaPharma Meet Us - Make an Appointment

Diapharma Find Your Territory Manager


we deliver solutions

It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma olivia matt mike

Visit diapharma.com

Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01102Rev01

Highest Quality Assays for IVIG and Albumin Safety Testing

Fibrinolysis Assays from DiaPharma that will enhance your research

Reliable testing for procoagulant contaminants

To reduce the risk of thromboembolic events, manufacturers need reliable assays to test procoagulant contaminants in IVIG and Albumin preparations.

DiaPharma offers a variety of products for sensitive quality control and safety testing for detection of potential thrombogenic activity.

Prekallikrein Activity Assays

Specialty Range of PKA Assay Kits, Reagents & Controls

Fractionation of Human plasma to produce Human Albumin and Immunoglobulin preparations can result in concentration of PKA. DiaPharma is excited to offer the highest quality PKA assay kits and reagents.

Featured Product: Human Prekallikrein Pool

  • Save time and repeat runs with this ready to use, convenient, reproducible Human Prekallikrein Pool.
  • Prepared according to the procedure recommended by the European Pharmacopoeia (EP) for assays of Prekallikrein Activator (PKA).

 


ROX FXIa

(110050)

Chromogenic kit for determination of low levels of FXIa in enriched or highly purified protein

  • The most sensitive kit on the market
  • Low interference – ideal for in-process and final testing of immunoglobulin preparations
  • Reagents comprise highly purified components

rossix rox factor Xia

rossix rox factor Xia


technothrombin TGA thrombin generation assay ivig kit

Technothrombin TGA IVIG

(5006218)

Specially designed trigger reagent with phospholipid and tissue factor concentration optimized for IVIG preparation testing

Ceveron c100


 

Chromogenic substrates

S-2302 (S820340)

  • Prekallikrein, kallikrein inhibitors, FXII, prekallikrein activators in albumin and immunoglobulin preparations

S-2366 (S821090)

  • FXI, APC
S-2238 (S820324)

  • Thrombin, prothrombin, antithrombin

S-2288 (S820852)

  • Broad spectrum of serine proteases

 


All products are for research use only in the U.S. and Canada. Not for use in diagnostic procedures.


Diapharma Jen Mike

The DiaPharma team brings a deep knowledge base and strong technical expertise to every customer interaction. Questions about any product in our lineup? We’re just a click or phone call away.

800.526.5224 | info@diapharma.com | diapharma.com

ML-00-01095Rev01


8948 Beckett Rd 45069 West Chester US

Comprehensive Solutions for von Willebrand Disease Research

It’s Not Just Support. It’s Solutions.


diapharma

Explore Assays from DiaPharma to Enhance Your

von Willebrand Disease Research

Reagent-complete kits for vWF Activity, Antigen, Collagen Binding, Propeptide, and more.

FEATURED PRODUCTS

Technozym vWF:CBA*

  • Collagen Binding ELISA
  • Ask your Territory Manager about a free evaluation kit through September!

Technozym vWF:CBA von willebrand factor collagen binding assay kit

Inter Array vWF:pp*

  • Standardized Propeptide ELISA
  • Ready-to-use complete kit

Ordering Info:

Product Description REF
REAADS vWF Activity ELISA vWF Activity K10826
REAADS vWF Antigen ELISA vWF Antigen K034-001
TECHNOZYM® vWF:CBA ELISA* vWF:CB 5450301
TECHNOZYM® vWF:CBA Calibrator Set* Calibrator 5450310
TECHNOZYM® vWF:CBA Control Set* Control 5450312
TECHNOZYM® vWF:Ag ELISA Kit* vWF Antigen 5450201
TECHNOZYM® vWF:Ag Calibrator Set* Calibrator 5450210
TECHNOZYM® vWF:Ag Control Set* Control 5450212
Inter Array vWFpp ELISA* vWF propeptide (vWFpp) Antigen 13.2.095.0096
T-TAS® 01 Microfluidic Clot Occlusion Instrument 18001
Coamatic® Factor VIII Chromogenic Factor VIII K822585
Coatest® SP Factor VIII Chromogenic Factor VIII K824086
Coatest® SP4 Factor VIII Chromogenic Factor VIII K824094
Rox Factor VIII* Chromogenic Factor VIII 800070
Technochrom® Factor VIII* Chromogenic Factor VIII 5344101

* For research use only. Not for use in diagnostic procedures.

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


DiaPharma specializes in clinical and research products for:

coagulation & fibrinolysis markers thrombo-inflammatory markers hemostasis analyzers anticoagulation measurement


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise is just a call or click away.

DiaPharma platelet function testing Coagulation + Fibrinolysis Marker Assays Thrombo-inflammation Marker Assays Anticoagulation Measurement Kits and Reagents Do-it-all Coagulation Analyzers Biomarker assays early detection of liver injury during AAV gene therapy trials

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01093Rev01

Clot Club #47

A REVIEW OF THE XXXVTH INTERNATIONAL SYMPOSIUM ON TECHNICAL INNOVATIONS IN LABORATORY HEMATOLOGY 2023 (ISLH 2023)

Comprehensive Solutions for Your Fibrinolysis Research

It’s Not Just Support. It’s Solutions.


 Fibrinolysis Assays from DiaPharma that will enhance your research

Fibrinolysis Assays

from DiaPharma that will enhance your research

Whether you’re researching basic fibrinolysis mechanisms or investigating new potential thrombolytics, you need reliable, relevant tests. DiaPharma can help you select the right assays.

technozym PAI Antigen ELISA t-PA Antigen ELISA PAP complex ELISA

Featured Products:

Technoclone tPA Purified Protein

  • Single chain tissue type plasminogen activator (human, recombinant),with activity at least 300,000 IU/mg.

Technozym® PAI-1 Actibind® ELISA

  • Quantitative determination of active PAI-1 antigen in human plasma

Technozym® PAP Complex ELISA

  • Plasmin-α-2-antiplasmin (PAP) complex ELISA
  • Detect elevated levels in hyperfibrinolysis and thrombolytic research.

View our full portfolio at diapharma.com.

All products are for research use only in U.S. and Canada. Not for use in diagnostic procedures.

tPA, PAI-1, P-AP, D-Dimer

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


DiaPharma specializes in clinical and research products for:

coagulation & fibrinolysis markers thrombo-inflammatory markers hemostasis analyzers anticoagulation measurement


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise is just a call or click away.

DiaPharma olivia matt mike

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01096Rev01

 

Comprehensive Solutions for Anticoagulation Research

It’s Not Just Support. It’s Solutions.


diapharma

Explore Assays from DiaPharma to Enhance Your Anticoagulation Research

Whether you’re researching vitamin K antagonists, thrombin inhibitors, FXa inhibitors, or contact pathway inhibitors, you need reliable, relevant tests. DiaPharma can help you select the right assays.

DOAC-STOP, DOAC-TEST, Inhibitor Tubes

DOAC-STOP™ Tablets*

THE original DOAC eliminator

  • Don’t be fooled by copies – DOAC-STOP™ is THE original DOAC neutralizer
  • Effectively eliminate interference from DOACs in plasma to get accurate results
  • Perform clotting assays on plasma containing DOACs in anticoagulant research
  • Also available: DOAC-Stop™ L (liquid for dispersion in whole blood) and DOAC-Stop™ µ* (for pediatric and small sample sizes). Contact us for samples!

 

Inhibitor Tubes*

Simplify your laboratory’s research needs

  • Inhibitor Tubes can be used to prepare known positive samples for clotting and chromogenic assays.
  • Inhibitor Tubes provide a pre-determined quantity of a DOAC coagulation inhibitor for delivery to a blood, plasma or urine sample in a tube – an alternative to lyophilized normal plasmas

inhibitor tubes

MORE FROM DIAPHARMA:

DOAC Calibrators & Controls*

  • High quality calibrators and controls for the reliable measurement of Apixaban ● Rivaroxaban ● Edoxaban ● Arixtra ● Dabigatran

Anti-Xa Assay Kits

  • Chromogenic anti-Xa kits to measure measure Low Molecular Weight Heparin (LMWH), Unfractionated Heparin (UFH), and direct FXa inhibitors
  • Coamatic® Heparin, Coatest® Heparin, and Technochrom anti-Xa* to suit your needs

*For research use only. Not for use in diagnostic procedures.

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


DiaPharma specializes in clinical and research products for:

coagulation & fibrinolysis markers thrombo-inflammatory markers hemostasis analyzers anticoagulation measurement


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise is just a call or click away.

DiaPharma platelet function testing Coagulation + Fibrinolysis Marker Assays Thrombo-inflammation Marker Assays Anticoagulation Measurement Kits and Reagents Do-it-all Coagulation Analyzers Biomarker assays early detection of liver injury during AAV gene therapy trials

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01086Rev01

Clot Club #46

ISTH 2023 BLOG COMPILATION

Nothing but NETs…Introductory pricing for Nu.Q® Discover H3.1 ELISA Research Use Only Kit

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

DiaPharma now offers the

Volition Nu.Q® Discover H3.1 ELISA

DiaPharma is excited to announce a new relationship with VolitionRx Ltd to provide the Nu.Q® Discover H3.1 ELISA in the U.S. and Canada.

Volition’s Nu.Q® Discover H3.1 ELISA Research Use Only kit detects quantitative levels of circulating intact nucleosomes containing Histone H3 in plasma. This kit is the first standardized, off-the-shelf, commercial option available for NETosis clinical research.

In honor of a successful and NET-focused ISTH 2023, ask us about our limited Nu.Q® Pricing offer available now through September.

Diapharma Find Your Territory Manager

Volition Nu.Q® Discover H3.1 ELISA quantitative levels of circulating intact nucleosomes containing Histone H3 in plasma NETosis clinical research

This ready-to-use ELISA kit includes standards and requires no further assay development

The Nu.Q® Discover H3.1 ELISA Research Use Only kit is a powerful research tool for a wide range of research areas that study nucleosomes and neutrophil extracellular traps (NETs) such as:

  • Coagulation
  • Thromboinflammation
  • Oncology
  • Sepsis
  • Auto-immune Diseases
  • Neurodegenerative Diseases
  • Inflammatory Disease
  • NETopathies (neutrophil extracellular trap associated diseases)
  • COVID-19

For Research Use Only. Not for use in diagnostic procedures.

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01082Rev01

Thank You for connecting with DiaPharma at AACC – ADLM 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

THANK YOU FOR CONNECTING WITH US

AT ADLM (AACC) Clinical Lab Expo 2023

We enjoyed discussing the hottest topics in Coagulation, NETs, Neutrophil Elastase Activity testing, MMPs, the all-in-one Ceveron® s100*, and the latest technology in platelet function measurement, featuring the FDA-cleared T-TAS® 01 PL Assay.

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

DiaPharma provides:

  • Innovative solutions to profiling nucleosomes
  • Neutrophil Elastase Assays
  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Anti-Hemoglobin antibodies for Sickle Cell Disease research
  • Biomarkers for early detection of liver injury during AAV gene therapy trials

Connect with a DiaPharma Scientist

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01083Rev01

Clot Club #45

EARLY INSIGHTS FROM RSA 2023

Clot Club #44

THROMBOSIS AND HEMOSTASIS IN LIVER DISEASE AND KIDNEY DISEASE: A CALL FOR MORE RESEARCH

Thank you for connecting with DiaPharma at ISTH 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Thank you for connecting with us at ISTH

We enjoyed seeing old friends and meeting new acquaintances at the ISTH 2023 Congress in Montréal last month. We learned the latest on all things bleeding & clotting, and had the opportunity to demonstrate the all-in-one Ceveron® s100* along with new technology in platelet function measurement, featuring the T-TAS® 01 and Atlas PST. We also had the pleasure of announcing our new relationship with Volition to provide the Nu.Q® Discover H3.1 ELISA to our North American friends.

Ceveron s100* platelet function measurement, T-TAS 01 Atlas PST. Volition Nu.Q Discover H3.1 ELISA

Our team will be reaching out to provide specific product information. We invite you to connect with a DiaPharma scientist with any questions as well.

Connect with a DiaPharma Scientist

DiaPharma provides:

  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Marker Assays
  • Thrombo-inflammation Marker Assays
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Biomarker assays for early detection of liver injury during AAV gene therapy trials

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

DiaPharma platelet function testing Coagulation + Fibrinolysis Marker Assays Thrombo-inflammation Marker Assays Anticoagulation Measurement Kits and Reagents Do-it-all Coagulation Analyzers Biomarker assays early detection of liver injury during AAV gene therapy trials

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01079Rev01

Connect with DiaPharma at AACC 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

STOP BY OUR BOOTH 4047 TO CONNECT WITH US
AT AACC Clinical Lab Expo 2023

We would love to see old friends and meet new acquaintances at the AACC 2023 Clinical Lab Expo, July 25 – 2 – 27 in Anaheim.

Our team is eager to talk about the latest in Coagulation, NETs, Neutrophil Elastase Activity testing, MMPs, and more! Demo the all-in-one Ceveron® s100 along with new technology in platelet function measurement, featuring the Atlas PST* and the FDA-cleared T-TAS® 01.

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays factor ix xia xiii tpa anticoag testing doac-stop measurement complement c1 inhibitor macro 163 cd163 ceveron s100 tga t-tas atlas pst

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Talk with us about:

  • Innovative solutions to profiling nucleosomes
  • Neutrophil Elastase Assays
  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Anti-Hemoglobin antibodies for Sickle Cell Disease research
  • Biomarkers for early detection of liver injury during AAV gene therapy trials

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01060Rev01

Gordon Research Conference (GRC) Cellular & Molecular Mechanisms of Toxicity (CMMT 2023)

DiaPharma 2023 Cellular & Molecular Mechanisms of Toxicity (CMMT) Gordon Research Conference (GRC)

DiaPharma is a proud to support the 2023 Cellular & Molecular Mechanisms of Toxicity (CMMT) Gordon Research Conference (GRC).

Clot Club #43

ATS THOUGHTS FROM A SECOND-TIMER– OLIVIA STRICKER, PhD

Don’t Miss Out – Complimentary Webinar on Neutrophils in Sputum: Why Give a Spit?

It’s Not Just Support. It’s Solutions.


 diapharma

It’s Almost Here!

Neutrophils in Sputum:

Why Give a Spit?

Wednesday, July 12 at 11 a.m. EDT

Please join DiaPharma for a complimentary educational webinar on the benefits of using sputum samples to take an accurate picture of neutrophil-driven immune responses in the lung.

register

sputum samples neutrophil-driven immune responses in the lung

Speaker Neil Alexis, Ph.D. of UNC Chapel Hill will discuss:

  • What are the advantages of sputum samples vs. other types of lung samples
    such as BAL?
  • What makes a high-quality sputum sample?
  • What can or should be measured in sputum?
  • Induced vs. Spontaneous Sputum – key differences – time and place for each.
  • Induced Sputum: “I heard it’s hard to do”… no, but it’s easy to do poorly.
  • Novel Sputum method: Home collection with delayed lab processing – encouraging data.
  • Intro to NELF- Nasal Epithelial Lining Fluid – a noninvasive method of sampling for chronic lung disease biomarkers

To register, visit diapharma.com.

REGISTER DIAPHARMA

DiaPharma is the US and Canadian distributor of the ProAxsis ProteaseTag® Active Neutrophil Elastase Immunoassay and is hosting this webinar to spotlight the importance of neutrophilic activity in the lung and the tools available to measure it. Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma Pulmonary Research Products


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,

with support just a call or click away.

Connect with a DiaPharma Scientist

diapharma.com


Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01065Rev01

Complimentary Webinar: Intro to Sputum and Nasal Epithelial Lining Fluid (nELF) Sampling

It’s Not Just Support. It’s Solutions.


 sputum and nELF sampling methods

register

Mucus throughout the lung and airway can provide insight into immune responses to different insults. Join DiaPharma and Dr. Neil Alexis on Wednesday, July 12 at 11 AM EDT to learn about sputum and nELF sampling methods and the value that can be gleamed from analyzing biomarkers in these fluids (or not so fluid if you are doing it right!).

sputum and nELF sampling methods

Neil Alexis, PhD., Professor, Dept. of Pediatrics, Division of Allergy, Immunology and Rheumatology at UNC Chapel Hill’s Center for Environmental Medicine, Asthma and Lung Biology (CEMALB)

About the Speaker: Dr. Alexis’s research is focused on examining the underlying pathophysiologic mechanisms of pulmonary diseases such as asthma, COPD and CF. Specifically, he is interested in the immune response in the airways using induced sputum as a primary sampling tool for measuring cellular, biochemical and genetic outcomes in the airways of human subjects. Dr. Alexis also supervises a biorepository of over 750,000 human biospecimens that supports CEMALB investigators, UNC collaborators, industry sponsors, and external investigators.

REGISTER DIAPHARMA

diapharma


Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01064Rev01

Relevant topic in a time of wildfire smoke: Neutrophils in Sputum – Webinar July 12th

It’s Not Just Support. It’s Solutions.


diapharma

Complimentary Webinar

Neutrophils in Sputum:

Why Give a Spit?

Wednesday, July 12 at 11 a.m. EDT

register

sputum samples neutrophil-driven immune responses in the lung

Over this past week, many of us in the Midwest and East are experiencing terribly low air quality due to the Canadian wildfires. A webinar on assessing neutrophil activity in the lung therefore could not be more relevant.

Dr. Neil Alexis has performed much of the research behind the air quality ranges established in the US today. Along with striving to understand environmental exposures (e-cigarettes, wood fire, burn pits, ozone, etc.) on the healthy lung, he aims to understand how those insults contribute to triggers on a background of pulmonary disease.

Please join DiaPharma and Dr. Alexis for a webinar covering sampling methods to measure the activity of immune cells, particularly neutrophils, in the lung.

To register, visit diapharma.com.

REGISTER DIAPHARMA


Learn about DiaPharma’s portfolio of products for pulmonary research

Diapharma Pulmonary Research Products

Connect with a DiaPharma Scientist


Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01063Rev01

Webinar Alert: Neutrophils in Sputum: Why Give a Spit?

It’s Not Just Support. It’s Solutions.


 diapharma

Complimentary Webinar

Neutrophils in Sputum:

Why Give a Spit?

Wednesday, July 12 at 11 a.m. EDT

Please join DiaPharma for a presentation on the benefits of using sputum samples to take an accurate picture of neutrophil-driven immune responses in the lung.

register

neutrophil-driven immune responses in the lung. Respiratory Research Products From DiaPharma

Speaker Neil Alexis, Ph.D. of UNC Chapel Hill will discuss:

  • What are the advantages of sputum samples vs. other types of lung samples
    such as BAL?
  • What makes a high-quality sputum sample?
  • What can or should be measured in sputum?
  • Induced vs. Spontaneous Sputum – key differences – time and place for each.
  • Induced Sputum: “I heard it’s hard to do”… no, but it’s easy to do poorly.
  • Novel Sputum method: Home collection with delayed lab processing – encouraging data.
  • Intro to NELF- Nasal Epithelial Lining Fluid – a noninvasive method of sampling for chronic lung disease biomarkers

To register, visit diapharma.com.

REGISTER DIAPHARMA

DiaPharma is the US and Canadian distributor of the ProAxsis ProteaseTag® Active Neutrophil Elastase Immunoassay and is hosting this webinar to spotlight the importance of neutrophilic activity in the lung and the tools available to measure it.

Research use only in U.S. and Canada. Not for use in diagnostic procedures.


Learn more about DiaPharma’s portfolio of products for pulmonary research

Diapharma Pulmonary Research Products


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,

with support just a call or click away.

Connect with a DiaPharma Scientist

Diapharma Jen Mike

diapharma.com

Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01058Rev01

Connect with DiaPharma at ISTH 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

 

STOP BY OUR BOOTH 1028 TO CONNECT WITH US AT ISTH 2023

We would love to see old friends and meet new acquaintances at the ISTH 2023 Congress, June 24 – 28 in Montréal. Our team is eager to talk all things bleeding & clotting, and demo the all-in-one Ceveron® s100* along with new technology in platelet function measurement.

We also invite you to our partner Technoclone’s Presentation Theatre, “A New Dawn in FVIII Inhibitor Testing” on Tuesday, June 27.

Factor VIII Inhibitor Testing

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Talk with us about:

  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Biomarkers for early detection of liver injury during AAV gene therapy trials

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Endothelial Cell activation chromogenic assays anticoagulation testing ceveron s100 t-tas 01 complement

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01052Rev01

Supporting International NASH Day

It’s Not Just Support. It’s Solutions.

M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

DiaPharma supports International NASH Day 2023

June 8, 2023 is International NASH Day. NASH Day raises visibility and urgency around fatty liver disease and its more advanced form, non-alcoholic steatohepatitis (NASH).

Non-alcoholic fatty liver disease (NAFLD) and NASH have few outward symptoms, and patients are often undiagnosed. However, recognized risk factors that are associated with NASH include obesity, type 2 diabetes, and hyperlipidemia. There are currently no approved pharmacologic therapy options for treating NASH. Promoting visibility and improving early detection are important steps to reduce the global prevalence of this disease.

DiaPharma supports NASH drug development by offering noninvasive tests (NITs) for biomarkers like Cytokeratin 18 (CK18) that provide early, biologically plausible indications of changes in disease activity. We believe that the future is bright and that safe and effective treatment options are within reach, with many promising candidates on the horizon.

Visit DiaPharma and VLVbio™ in the Biotech Village at the EASL Congress™ 2023

June 21 – 24 in Vienna

DiaPharma offers additional non-invasive biomarker assays for NAFLD/NASH, AH, and DILI research. Incorporating these biomarkers into your research adds valuable information about changes in disease activity, which could decrease time and costs of studies. M30® and M65® Cytokeratin 18 (CK18) ELISAs, Intact Proinsulin, sCD163, L-FABP, and FGF-21 are just a few of the biomarker assays offered by DiaPharma to help your drug candidate move forward.

If you’d like to speak with an expert about which biomarker would be most useful for your project, call 800.447.3846 or email us today.

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Connect with a DiaPharma Scientist

Diapharma Find Your Territory Manager


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Technical Support: 1.800.447.3846

ML-00-01057Rev01

Webinar Alert: “The role of inflammation in the vicious vortex of bronchiectasis – is it time to re-evaluate?”

It’s Not Just Support. It’s Solutions.

lung-specific measurements of inflammation neutrophil elastase (NE), proteinase 3 (PR3), collagen, keratin 18

Complimentary Webinar Alert!

Inflammation and Bronchiectasis

June 8th, 2023 at 10 am EDT

register

lung-specific measurements of inflammation neutrophil elastase (NE), proteinase 3 (PR3), collagen, keratin 18

DiaPharma is always on the lookout for educational opportunities. Insmed is hosting an informative and interactive webinar from Dr. James Chalmers on inflammation and bronchiectasis on Thursday, June 8 at 10 am Eastern.

“The role of inflammation in the vicious vortex of bronchiectasis – is it time to re-evaluate?”

REGISTER DIAPHARMA

What: Insmed is hosting an educational and interactive webinar from Dr. James Chalmers on inflammation and bronchiectasis on Thursday, June 8 at 10 am Eastern.

Why: As someone interested in lung disease and biomarkers, DiaPharma thought this webinar might be of interest to you.

Details: Insmed has published some positive data with their brensocatib trial using the ProAxsis ProteaseTag® Active Neutrophil Elastase and Proteinase 3 Immunoassays, which are distributed in the US and Canada by DiaPharma.

Brensocatib is a drug being developed by Insmed for the treatment of bronchiectasis. Brensocatib may decrease the damaging effects of inflammatory diseases by inhibiting DPP1 and its activation of neutrophilic proteases, like neutrophil elastase and proteinase 3. Active Neutrophil Elastase can be measured to endotype for bronchiectasis research and is used in current trials as a biomarker for enrichment, mechanism, and efficacy.

So join us as we learn about the role of inflammation in bronchiectasis this Thursday!

Research use only in U.S. and Canada. Not for use in diagnostic procedures.


Learn more about DiaPharma’s complimentary portfolio of products for pulmonary research

Diapharma Pulmonary Research Products


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,
with support just a call or click away.

Connect with a DiaPharma Scientist

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Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

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International Society on Thrombosis and Haemostasis (ISTH) Congress 2023

DiaPharma will be exhibiting at ISTH and would love for you to stop by our booth.  In addition to showing off the newest FDA cleared  PL Chip test for Total Thrombus formation Analysis System (T-TAS®), we will be sharing details on the new technology entering the research market related to platelet function testing and special coag.   Please contact us to connect with our DiaPharma team members or schedule an instrument demo.

 

DiaPharma ISTH 2023

American Diabetes Association 2023

DiaPharma has never been to ADA, but is excited to learn more about what biomarkers are important for diabetes research.  We offer the Intact Proinsulin ELISA* from TECO Medical and we are interested to understand how it could be useful for T1D and T2D research or clinical trials.  Please contact us to connect with our DiaPharma team members.

*For Research Use Only.  Not for use in diagnostic procedures.

DiaPharma ADA 2023

EASL – THE INTERNATIONAL LIVER CONGRESS™

The liver is DiaPharma’s wheelhouse so we encourage you to set up a meeting with us or our partners at VLVbio to discuss how their liver injury marker, CK18*, can be useful in NASH, alcohol-associated liver disease, and drug safety research.  We are always interested in learning the latest and staying in touch with researchers and clinicians in the field.  Please contact us  to connect with our DiaPharma or VLVbio team members.

*For Research Use Only.  Not for use in diagnostic procedures.

DiaPharma EASL 2023

DiaPharma Celebrates hae day :-)

It’s Not Just Support. It’s Solutions.

diapharma

May 16 is hae day 🙂

Join DiaPharma in raising awareness, step by step

The annual hae day 🙂 aims to raise awareness worldwide of HAE. Team DiaPharma is getting #Active4HAE! Join us by logging time spent on physical or well-being activities at haeday.org.

Read about emerging therapeutic targets for HAE at diapharma.com.

diapharma clot club blog


Explore Assays from DiaPharma for Gene Therapy and Cell Therapy Research in Rare Diseases

HEREDITARY ANGIOEDEMA (HAE)

Technochrom® C1-INH*

  • Chromogenic C1 Esterase Inhibitor (C1-INH) activity
  • Easy, automatable, simple and fast assay for chromogenic determination of C1-INH activity in plasma or concentrates

Thrombin Generation Testing*

  • Technothrombin® TGA
  • Ceveron®* for TGA and all-in-one coagulation analyzer
    *For research use only. Not for use in diagnostic procedures.

Connect with a DiaPharma Scientist

Diapharma Find Your Territory Manager

diapharma gene therapy research products


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Over 25 years of scientific expertise,

with support just a call or click away.

Diapharma Jen Mike

diapharma

Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

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Collagen is tough (pun intended), make your life easier with these QuickZyme kits

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

 

DiaPharma and QuickZyme Know Matrix Matters!

For tissues with lower collagen levels and high matrix effect, analyzing collagen is difficult. QuickZyme therefore developed an assay in which the matrix effect was neutralized to make total collagen analysis suited for more organs or imbedded tissue. The references below are based on the sensitive tissue collagen assay and is focused on use in the liver, but their methods are applicable to a variety of organs, including heart, lung, kidneys and embedded tissue samples.

 

quickzyme soluble collagen assay sensitive tissue total collagen hydroxyproline

 

 DiaPharma Quick Guide

 

QuickZymeTotal Collagen Kit – hydroxyproline detection method details:

  • Compatible with many tissue digestion protocols
  • Wide detection range for accurate quantitation
  • Easy 2 hour protocol with no drying step
  • Application available for low collagen organs and paraffin imbedded tissue
  • Applicable to all species types

References:

van den Hoek AM, Verschuren L, Worms N, et al. A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology. Cells. 2020;9(9):2014. Published 2020 Sep 1. doi:10.3390/cells9092014

van den Hoek AM, de Jong JCBC, Worms N, et al. Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk. Metabolism. 2021;124:154873. doi:10.1016/j.metabol.2021.154873

Collagen assays available from QuickZyme Biosciences:

 

Make your life easier with these QuickZyme kits.

Research use only in the U.S. and Canada. Not for use in diagnostic procedures.

QuickZyme assay kits

LEARN MORE


diapharma

FATTY LIVER DISEASE

NAFLD/NASH

HEMOSTASIS

ALD/AH

DILI / TOXICOLOGY

DILI Research

CANCER RESEARCH

K18: M30®/M65®


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Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

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Why isn’t this being funded?! Product Grant Opportunity from DiaPharma

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Thoughts from HTRS 2023, and a Grant Opportunity

The HTRS 2023 Scientific Symposium gave new insights in hemostasis and thrombosis, from health justice initiatives to the latest in antiphospholipid antibody testing.

One thing that stood out was a focus on bleeding and clotting disorders in special populations such as pregnancy, pediatrics, Sickle Cell Disease, and bleeding disorders in women and girls. Addressing outcomes, assessing risk, and making sure patients have access to treatment are taking center stage.

Among the calls to action discussed during HTRS was the need to communicate and collaborate with colleagues. We need to improve awareness of platelet disorders, better characterize diagnosis and care, and better address the impacts of bleeding in women and girls.

DiaPharma cares about research benefiting underrepresented populations. We have decided to take a step and be part of this shift we’re seeing in the hemostasis field.

DiaPharma is now accepting research project proposals for a complementary T-TAS® 01 platelet function analyzer to study bleeding risk. We hope the award of a T-TAS® 01 analyzer helps further impactful research in our field.

DiaPharma Apply Here

Endothelial Cell Activation Chromogenic Assays Anticoagulation Testing Complement
*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

View our full portfolio of hemostasis and thrombosis assays, including vWF and ADAMTS13 panels, automated FXIII, APC Resistance, and unique antibodies for analysis of hemoglobinopathies, feto-maternal hemorrhage, and Rh incompatibility, at diapharma.com.

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01045Rev01

Are your patients getting the proper level of anticoagulation?

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Measuring Warfarin in Patients with a Lupus Anticoagulant

At the recent HTRS 2023 Scientific Symposium, a lively discussion in a Plenary Session was presented titled, “Do We Dare to DOAC?” in which presenters debated the use of DOACs in patients with antiphospholipid antibody syndrome (aPS).

For an in-depth review, read our April Clot Club post, “Should Direct Oral Anticoagulants (DOAC) be Used in Individuals with Antiphospholipid Syndrome (aPS) vs Long Term Warfarin Treatment?”

The topic brings up the questions:

  • Do LA/aPS patients always get the best anticoagulation treatments?
  • What are the options for monitoring a patient with the presence of a strong LA inhibitor, where INRs might be unreliable?
  • What test can measure the effect of warfarin to help ensure the patient is in therapeutic range?

The chromogenic FX assay can be used here to measure % FX. Chromogenic FX activity levels have shown utility for monitoring warfarin therapy in patients where INR is unreliable, such as in aPS (Rosborough & Shepherd, 2004).

The DiaPharma Factor X Kit is accessible, FDA cleared, and offered by reference labs across the U.S.

Visit diapharma.com to learn more.

DiaPharma Factor X Monitoring warfarin is a delicate balance
Monitoring warfarin is a delicate balance

Reference: Rosborough T.K., Shepherd M.F. Unreliability of international normalized ratio for monitoring warfarin therapy in patients with lupus anticoagulant. Pharmacotherapy. 2004;24(7):838–842.

View our full portfolio of hemostasis and thrombosis assays at diapharma.com.

Diapharma Find Your Territory Manager

Connect with a DiaPharma Scientist


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-01-00014Rev01

American Thoracic Society (ATS) 2023

DiaPharma will be exhibiting at ATS for the first time and is excited to meet key stakeholders in the pulmonary space.  We will be sharing details about the ProAxsis ProteaseTag® Active Neutrophil Elastase Immunoassay* for research and clinical trials along with QuickZyme MMP Activity* assays and collagen assays.  With all of the inflammation and fibrosis happening in lung disease, we are hoping these are helpful tools to add to the drug development toolbox in the respiratory landscape.  Please contact us to connect with our DiaPharma team members, Olivia Stricker and Tinu Adewole.

*For Research Use Only.  Not for use in diagnostic procedures.

DiaPharma ATS 2023

Clot Club #42

SOT 2023, RECAP THROUGH A DIAPHARMA LENS

WHD 2023

Today, April 17, is World Hemophilia Day. This year’s theme is “Access for All: Prevention of bleeds as the global standard of care”. DiaPharma supports access to information, treatment, and care for all people with bleeding disorders. Learn more and take action at https://wfh.org/world-hemophilia-day/.

#WHD2023
#WorldHemophiliaDay
#Hemophilia
#AccessForAll
#LightItUpRed


ML-00-01043Rev01

Clot Club #40

SHOULD DIRECT ORAL ANTICOAGULANTS (DOAC) BE USED IN INDIVIDUALS WITH ANTIPHOSPHOLIPID SYNDROME (APS) VS LONG TERM WARFARIN TREATMENT?

Clot Club #39

WHY ISN’T THIS BEING FUNDED?! THOUGHTS FROM HTRS 2023, AND A GRANT OPPORTUNITY FROM DIAPHARMA

Connect with DiaPharma at AACR 2023

It’s Not Just Support. It’s Solutions.


M30 Apoptosense M65 ELISAs cell death anti-tumor drugs

Connect with DiaPharma
at AACR 2023

We are eager to connect with the cancer research community at AACR 2023, and discuss the latest advances in the field. If you’re heading to Orlando, reach out to us to talk about your projects, the hottest conference topics, or what you’d like to see from industry.

Learn more about DiaPharma’s portfolio of assays for anti-cancer drug development, including M30 Apoptosense® + M65® ELISAs to identify mechanism of cell death in anti-tumor drugs.

M30 Apoptosense M65 EpiDeath M30 CytoDeath ELISA oncology research products, TK1, Osteopontin, Periostin, Noggin, Mac-2 Binding Protein.

Ask us about our full line of oncology research products, including TK1, Osteopontin, Periostin, Noggin, Mac-2 Binding Protein.

New this year: DiaPharma now has a comprehensive portfolio of IQProducts antibodies for use in flow cytometry analyses.

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01039Rev01

XXXVIth International Symposium on Technical Innovations in Laboratory Hematology (ISLH)

DiaPharma will be exhibiting at ISLH and would love for you to stop by our booth.  In addition to showing off the newest FDA cleared PL Chip test for Total Thrombus formation Analysis System (T-TAS®), we will be sharing details on the new technology entering the research market related to platelet function testing and special coag.   Please contact us  to connect with our DiaPharma team members or schedule an instrument demo.

 

DiaPharma ISLH 2023

Address Unmet Needs in Type 1 Diabetes Drug Development with These Biomarkers

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Type 1 Diabetes (T1D) biomarkers, islet auto-antibodies (AAs), insulin, GAD65, IA-2, ZnT8

How can blood-based biomarkers enrich your Type 1 Diabetes (T1D) study population?

In individuals at high risk for Type 1 Diabetes (T1D), the presence of two or more islet auto-antibodies (AAs), such as those to insulin, GAD65, IA-2, and ZnT8, has been shown to be predictive of the rate of disease progression. These islet AAs can be used together with other features to help identify individuals at highest risk for disease development.

In trials intended to prevent or delay the clinical diagnosis of T1D, including these biomarkers in the enrollment process can therefore aid in enriching the study population with subjects likely to progress to stage 3 disease within a reasonable time span. This may allow for smaller and shorter trials, leading to potential cost savings for the study sponsors.

Type 1 Diabetes (T1D) biomarkers, islet auto-antibodies (AAs), insulin, GAD65, IA-2, ZnT8

Leading Expertise in Type 1 Diabetes Research Assays

DiaPharma offers ELISAs from our partner Medipan GmbH for determination of islet AAs in human serum samples.

  • Medizym® Anti- GAD (35071) – antibodies against glutamic decarboxylase (GAD65)
  • Medizym® Anti- IA2 (35061) – antibodies against protein tyrosine phosphatase (insulinoma antigen-2, IA-2)
  • Medizym® IAA (38061) – IgG antibodies against insulin

These quantitative assays are easy to perform, and provide reproducible and reliable results.

  • Convenient: Ready-to-use, color- and barcoded reagents
  • Incubation at room temperature
  • Results expressed in IU/mL
  • Excellent sensitivity and specificity
  • High precision within the measurement range
  • Fully automatable

Contact your territory manager for an introductory offer!

Also available exclusively in North America from DiaPharma, TECO® Intact Proinsulin ELISA – Go with the Pro! Save time and guess work by selectively measuring only intact proinsulin.

All products are for research use only in the U.S. and Canada. Not for use in diagnostic procedures.

Diapharma Find Your Territory Manager


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,

with support just a call or click away.

Connect with a DiaPharma Scientist

Diapharma Jen Mike

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01022Rev01

Digestive Disease Week (DDW)

DiaPharma has never been to DDW, but it seems like a place we should be since we have tons of unique biomarkers for research in the liver and diabetes.  Please contact us  to connect with our DiaPharma team members.

 

DiaPharma DDW 223

Visit DiaPharma at ATS 2023 to discuss pulmonary markers in drug development

It’s Not Just Support. It’s Solutions.


 

Visit Booth 1232 at ATS 2023

to discuss mechanistic measurements for respiratory drug development

ADD DETAIL to a drug’s storyline with accurate and lung-specific measurements of inflammation like neutrophil elastase (NE), proteinase 3 (PR3), collagen, and keratin 18.

DiaPharma offers consumable products that measure novel biomarkers and are aimed to add value, by adding info, for respiratory drugs in development. We’re excited to share these unique tools for your respiratory research. Stop by our booth to chat!

  • Cystic Fibrosis
  • COPD
  • Bronchiectasis
  • Asthma
  • Idiopathic Pulmonary Fibrosis
  • Interstitial Lung Disease

Research use only in U.S. and Canada. Not for use in diagnostic procedures.


Learn more about DiaPharma’s complimentary portfolio of products for pulmonary research

Diapharma Pulmonary Research Products


It’s Not Just Support. It’s Solutions.

Celebrating 25 years of scientific expertise,

with support just a call or click away.

Connect with a DiaPharma Scientist

diapharma.com


Copyright © 2023 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01033Rev01

Thank You for Visiting DiaPharma at HTRS 2023

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diapharma

Thank you for connecting with us at HTRS 2023


The HTRS 2023 Scientific Symposium presented an opportunity to gain new insights in hemostasis and thrombosis, from health justice initiatives to lively and insightful debates (including apparently, how many steel mills there are in downtown Hamilton, Ontario).

Our DiaPharma team was pleased to speak with you about our testing solutions, including new technology in platelet function measurement. We hope you had a chance to enjoy some sun and fun as well!

Learn more about what DiaPharma has to offer:

T-TAS® 01 PL Assay: One test, one result, one answer for total platelet function. FDA cleared.

Atlas PST*: Discover a new dimension of platelet analysis. Uniquely measure platelet contractile forces to add data in a multitude of research applications.

View our full portfolio of hemostasis and thrombosis assays, including vWF and ADAMTS13 panels, at diapharma.com.

Connect with a DiaPharma Scientist

Endothelial Cell Activation Chromogenic Assays Anticoagulation Testing Complement

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

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Visit DiaPharma at ISLH 2023 in New Orleans

It’s Not Just Support. It’s Solutions.


diapharma

Connect with Us at ISLH 2023
Booth 102

We would love to see old friends and meet new acquaintances at ISLH 2023, May 11 – 13 in New Orleans. Our team is eager to talk all things bleeding & clotting, and demo new technology in platelet function measurement.

diapharma islh 2023

Stop by to discuss:

  • The latest platelet function testing solutions
  • Coagulation + fibrinolysis markers
  • Thrombo-inflammation markers
  • Anticoagulation measurement kits and reagents
  • Unique antibodies for analysis of hemoglobinopathies, feto maternal hemorrhage, and Rh incompatibility
  • Do-it-all coagulation analyzers
  • Hepatotoxicity biomarkers for early detection of liver injury

Endothelial Cell activation chromogenic assays anticoagulation testing ceveron s100 t-tas 01 complement
*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01027Rev01

Visit DiaPharma at SOT ToxExpo 2023

It’s Not Just Support. It’s Solutions.


 

STOP BY BOOTH 1209 TO CONNECT WITH US AT SOT TOXEXPO 2023

See us in Music City! Visit us March 20 – 22 to learn the latest in toxicology and explore the music scene.

We’re eager to talk liver and kidney injury biomarker assays for detecting safety signals in drug development, including Keratin 18 (K18/CK18), L-FABP, α-GST, NGAL, and Cystatin C.

Or, just drop by to argue with us about the best music genre.

Let’s discuss K18 assays, including the M65® EpiRat ELISA to assess hepatocyte cell death in drug development

  • Increased organ specific serum biomarker
  • Quantifies hepatocyte cell death to assess liver toxicity
  • Low day-to-day fluctuation and remarkably stable in serum

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01026Rev01

Visit DiaPharma at HTRS 2023 in Orlando

It’s Not Just Support. It’s Solutions.


diapharma

STOP BY OUR BOOTH TO CONNECT WITH US AT HTRS 2023

We would love to see old friends and meet new acquaintances at HTRS 2023, March 10 – 12 in Orlando, FL. Our team is eager to talk all things bleeding & clotting, and demo new technology in platelet function measurement.

Endothelial Cell Activation Chromogenic Assays Anticoagulation Testing Complement

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

Talk with us about:

  • The latest platelet function testing solutions
  • Coagulation + Fibrinolysis Markers
  • Thrombo-inflammation Markers
  • Anticoagulation Measurement Kits and Reagents
  • Do-it-all Coagulation Analyzers
  • Hepatotoxicity biomarkers for early detection of liver injury

Diapharma ISTH 2022

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic]

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01016Rev01

Anticoagulation Forum 17th National Conference

Coag is DiaPharma’s wheelhouse so we are heading to the Anticoagulation Forum.  We are always interested in learning the latest and staying in touch with researchers and clinicians in the field.  Please contact us to connect with our DiaPharma team members.

 

DiaPharma Anticoag Forum 2023

View the recording of “Shearly You Can’t Be Serious! T-TAS® 01 for Total Platelet Function”

It’s Not Just Support. It’s Solutions.


diapharma

Sorry you missed it! You can still view the recording.

Shearly you can’t be serious!

T-TAS® 01 for total platelet function

diapharma view the recording

T-TAS® 01 PL Assay:

One test, one result, one answer for total platelet function

Talk to a DiaPharma scientist today to learn more.


Connect with a DiaPharma Scientist

Diapharma Jen Mike

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-08-00052Rev01

Explore the Atlas PST – a New Dimension of Platelet Analysis

It’s Not Just Support. It’s Solutions.


diapharma

Stasys Atlas PST

Easy system for fast, accurate platelet function results

  • Designed to form microclots from whole blood samples to uniquely measure platelet contractile forces, aggregation, and function
  • Fast (< 3 minutes) and accurate results mean more information for your platelet function research
  • Reagents and agonists not needed – easy to bring in-house

LEARN MORE

 DiaPharma Stasys Atlas PST

DiaPharma Stasys Atlas PST

Top: The Stasys proprietary sensor technology measures the force of a formed microclot on the cellular level, and rapidly evaluates factors in the blood to assess coagulopathy.

Bottom: As the sample moves through the analysis chamber, microclots form and the force of the bond is measured.

Quickly detect all mechanisms of platelet dysfunction

  • Global assay of primary hemostasis measuring platelet clot strength
  • User-friendly device with small footprint (~1 sq ft) – rapid and self-contained testing
  • Minimal sample handling – no pipetting, no mixing
  • Report real-time data in under three minutes

DiaPharma Stasys Atlas PST

An individual sensor at the micron scale, and the shear gradients that it creates on passing streamlines of blood.

Add data in a multitude of research applications:

  • Research and drug development of potential therapeutics to restore primary hemostasis in e.g. ECMO subjects, anti-vWF agents, etc.
  • Bleeding risk / coagulopathy in trauma, sepsis, and DIC
  • Acute thrombosis (e.g. subjects with coronary artery disease before/after intervention, PAD, COVID, cancer-associated thrombosis)
  • Antiplatelet drug titration
  • Hereditary platelet disorders

For research use only in the U.S. and Canada. Not for use in diagnostic procedures.


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Connect with a DiaPharma Scientist

Diapharma Jen Mike

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DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-10-00010Rev01

Thank you for attending “Shearly You Can’t Be Serious! T-TAS® 01 for Total Platelet Function”

It’s Not Just Support. It’s Solutions.


diapharma

Thank you for attending

Shearly you can’t be serious!

T-TAS® 01 for total platelet function

diapharma view the recording

T-TAS® 01 PL Assay:

One test, one result, one answer for total platelet function

Talk to a DiaPharma scientist today to learn more.


Connect with a DiaPharma Scientist

Diapharma Jen Mike

Visit diapharma.com


DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-08-00051Rev01

Hemostasis and Thrombosis Research Society (HTRS) 2023 Scientific Symposium

Schedule a demo for the T-TAS®01 system or the Stasys Atlas platelet analyzer* or just stop by the DiaPharma table to say hello.  Please contact us  to connect with our DiaPharma team members or schedule a demo.

*For Research Use Only.  Not for use in diagnostic procedures.

 

Diapharma HTRS 2023

Emerging Biomarkers in Alcohol Associated Liver Disease

It’s Not Just Support. It’s Solutions.


  diapharma

Non-Invasive Biomarkers for Alcohol Associated Liver Disease Studies

Biomarkers of cell death and regeneration, inflammation, and immune response become useful tools as new potential Alcohol Associated Liver Disease (ALD) and Alcohol Associated Hepatitis (AH) treatment options are investigated. Serum biomarkers can provide valuable insights into:

  • Disease severity and progression in ALD and AH research studies
  • Mechanisms involved in ALD and AH pathogenesis

cell death, complement activation, liver regeneration fibrosis, immune response, ccCK18, M30 Apoptsosense, CK18, M65 EpiDeath, SCD163, NGAL, L-FABP

DiaPharma has the tools for ALD Research.

Measure hepatocyte apoptosis and/or necrosis with our Cytokeratin 18/Keratin 18 (CK18/K18) biomarkers:

Additional Biomarkers of Interest:

Also, ask us about the first commercial immunoassay kit to measure NETs in human plasma or serum on the market. Perfect for sepsis studies.

Visit diapharma.com for our comprehensive portfolio including biomarkers for Nonalcoholic Fatty Liver Disease (NAFLD) / Nonalcoholic Steatohepatitis (NASH) and Drug Induced Liver Injury (DILI).

All products are for research use only in the U.S. and Canada. Not for use in diagnostic procedures.

K18

liver disease research Nonalcoholic Fatty Liver Disease (NAFLD) / Nonalcoholic Steatohepatitis (NASH), Alcoholic Hepatitis (AH), Drug Induced Liver Injury (DILI)

Diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise,

with support just a call or click away.

Diapharma Jen Mike

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-01015Rev01

You name it, Ceveron® s100 can do it

It’s Not Just Support. It’s Solutions.


  diapharma

Discover the Ceveron® s100

The first fully-automated coagulation analyzer to combine classic technologies with high-powered LEDs for fluorescent and quenching resonance transfer assays. Perform clotting, chromogenic, and turbidometric hemostasis assays plus Thrombin Generation Testing, ADAMTS13 activity, and FXIII activity all with one instrument.

Learn More

Technoclone

Why Ceveron® s100?

  • Automate your FVIII, FXIII, C1-Inhibitor, ADAMTS13 activity, Thrombin Generation testing, and more
  • Lot-stable calibration and ease of for on-demand testing
  • Simultaneously run multiple assays and methods

Research use only in U.S. and Canada. Not for use in diagnostic procedures.

 Diapharma connect

Endothelial Cell Activation Chromogenic Assays Anticoagulation Testing Complement

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

diapharma


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-07-00045Rev01

 

Axes, Rage, and VR at DiaPharma?

It’s Not Just Support. It’s Solutions.


  diapharma

Kicking off 2023

Axes, rage, and VR at DiaPharma? At our national sales meeting, there is!

DiaPharma held our national sales meeting in January – it’s a chance to see each other in person, plan the year ahead, and have some fun! DiaPharma staff tried our hands at axe throwing, virtual reality, and “rage room”. Congrats to customer service specialist Amy on her bullseye!

genesis amy

rage

Meet us in person at the following events:

  • Hemostasis and Thrombosis Research Society (HTRS) Scientific Symposium: March 10 – 12 in Orlando, FL
  • Society of Toxicology (SOT) ToxExpo: March 20 – 22 in Nashville, TN
  • Anticoagulation Forum: April 1 – 3 in San Francisco, CA
  • American Association for Cancer Research (AACR): April 14 – 19 in Orlando, FL
  • International Society for Laboratory Hematology (ISLH): May 11 – 13 in New Orleans, LA
  • American Thoracic Society (ATS): May 19 – 24 in Washington, DC
  • International Society for Thrombosis and Hemostasis (ISTH): June 24 – 28 in Montréal, Quebec

Diapharma Meet Us - Make an Appointment

Diapharma Find Your Territory Manager

we deliver solutions

It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Diapharma Jen Mike

Visit diapharma.com

Copyright © 2022 DiaPharma Group, Inc. All rights reserved.

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01012Rev01

Complimentary Webinar: “Shearly You Can’t Be Serious! T-TAS® 01 for Total Platelet Function”

It’s Not Just Support. It’s Solutions.


  diapharma

You’re invited to a complimentary webinar:

Shearly you can’t be serious!

T-TAS® 01 for total platelet function

 

REGISTER DIAPHARMA

total platelet function

T-TAS® 01 PL Assay:

One test, one result, one answer for total platelet function

Help address staffing and budgetary challenges with a frontline test for overall total platelet function

  • Detects dysfunction due to anti-platelet therapy, and impaired primary hemostasis such as von Willebrand Disease (vWD)
  • Activated by shear stress, not agonist
  • Simultaneously handles multiple samples
  • Useful and easy-to-interpret results
  • Improve efficiency of additional testing
  • Provide more information than a pathway-specific test

T-TAS

REGISTER DIAPHARMA


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Connect with a DiaPharma Scientist

diapharma bioassays hemostasis thrombosis chromogenic

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-08-00049Rev01

Clot Club #38

CHOOSING WISELY – COAGULATION TESTING RECOMMENDATIONS

Complimentary Webinar: “Shearly You Can’t Be Serious! T-TAS® 01 for Total Platelet Function”

It’s Not Just Support. It’s Solutions.


  diapharma

You’re invited to a complimentary webinar:

Shearly you can’t be serious!

T-TAS® 01 for total platelet function

REGISTER DIAPHARMA

total platelet function

T-TAS® 01 PL Assay:

One test, one result, one answer for total platelet function

Help address staffing and budgetary challenges with a frontline test for overall total platelet function

  • Single assay with easy-to-interpret test result provides simple and comprehensive platelet reactivity status
  • Get a better clinical picture using true physiological flow/shear rates
  • T-TAS® 01 analyzer is low-cost, takes up modest space in the lab, and is uncomplicated to learn and operate
  • Allows direct comparison of the effect of antiplatelet therapies across different combinations and classes (i.e. aspirin ± P2Y12 inhibitors)

T-TAS

REGISTER DIAPHARMA


It’s Not Just Support. It’s Solutions.

Over 25 years of scientific expertise, just a call or click away.

Connect with a DiaPharma Scientist

diapharma bioassays hemostasis thrombosis chromogenic

Visit diapharma.com

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-08-00047Rev01

Clot Club #37

A STEEEEP LEARNING CURVE: MY TAKE HOME MESSAGES FROM AN ALCOHOL-ASSOCIATED LIVER DISEASE MEETING FROM A NEWBIE

Clot Club #36

THE DEBATE OF EARLY-LIVER TRANSPLANTATION FOR ALCOHOL-ASSOCIATED LIVER DISEASES

Because matrix matters! The path to lung disease is paved with MMPs and collagen

It’s Not Just Support. It’s Solutions.


  diapharma

DiaPharma and QuickZyme Know Matrix Matters!

QuickZyme specializes in collagen assays and MMP activity assays (MMP-2, MMP-7, MMP-8, MMP-9, MMP-14). These assays were developed by scientists to fill an unmet need as an alternative to laborious methods. The assays give a more granular insight to the role that extracellular matrix remodeling can play in fibrosis, inflammation, and metastatic tumors.

MMPs degrade collagen, elastin, and proteoglycans. As indicators of inflammation and disease, they are key targets for drug development.

  • Idiopathic pulmonary fibrosis (IPF): MMP-7 plays a role in the development of scarring in the lungs and may predict a decline of lung function.
  • Chronic obstructive pulmonary disease (COPD): Circulating MMP-9 is linked with increased exacerbation risk.
  • Cystic fibrosis (CF): MMP-7, MMP-8, and MMP-9 may play an important role in the injury/repair response in CF.
  • Lymphangioleiomyomatosis (LAM): MMP-2 and MMP-7 are expressed and contribute to the destruction of lung tissue in LAM.
  • Cigarette smoke: MMP-1, -2, -7, -9 and -12 have all been implicated in tissue damage due to cigarette smoke, but MMP-12 has been the most extensively studied.

Finally, a test to accurately and specifically quantify MMP activity in relevant biological samples (blood, sputum, urine, cell cultures, etc.). These kits make testing more efficient, with a dual readout option: Measure endogenous active (naturally occurring) or total (active + pro) MMP for each plate.

QuickZyme

Learn More


Make your life easier with these QuickZyme MMP Activity Assays:

Research use only in the U.S. and Canada. Not for use in diagnostic procedures.


More to Explore

DiaPharma offers an extensive portfolio of pulmonary biomarkers, including Cytokeratin 18 (CK18, K18) ELISAs – M30® and M65®, ProAxsis Neutrophil Elastase Activity Kit, IMD Neutrophil Elastase ELISA Kit, ProAxsis Proteinase 3 Activity Kit, IMD Proteinase 3 ELISA kit, Quickzyme Total Collagen Kit, IMD Alpha 1 Antitrypsin (A1AT), and IQ Macro163™ ELISA.

READ MORE


diapharma

It’s Not Just Support. It’s Solutions.

Celebrating 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-01000Rev01

Connect with DiaPharma at ASH 2022 in New Orleans

It’s Not Just Support. It’s Solutions.


  diapharma

SEE US AT ASH 2022!

DiaPharma continues to celebrate 25 years in the hemostasis and coagulation field – team members will be attending ASH 2022 in New Orleans this year. Our goal is to learn all the new things and meet up with existing and potential customers.

We’re interested in topics like:

  • Gene therapy studies related to hemophilia, sickle cell disease, hereditary angioedema
  • TMA updates and therapeutic strategies
  • Platelet function related to thrombocytopenia
  • Bleeding and clotting disorders
  • Hemophilia diagnostics and treatment strategies

Reach out to Ryan McCaw or Elizabeth Mihal to set up a conversation about:

  • ADAMTS13 assays for activity, antigen or inhibitor testing*
  • The Total Thrombus formation Analysis System (T-TAS®) 01 for an IVD global platelet function test
  • Chromogenic FVIII and FIX* activity testing
  • HbS and HbF antibodies for flow cytometry
  • The ATLAS PST* system for unique platelet function testing based on contractile force measurements and machine learning

*For research use only. Not for use in diagnostic procedures.

Our team is eager to talk all things bleeding & clotting, and demo new technology in platelet function measurement.

Diapharma ISTH 2022

endothelial cell activation adamts13 vwf factor viii platelet function chromogenic assays anticoagulation testing doac complement c1-inhibitor macro163

*Research use only in U.S. and Canada. Not for use in diagnostic procedures.

diapharma


It’s Not Just Support. It’s Solutions.

Celebrating 25 years of scientific expertise, just a call or click away.

diapharma bioassays hemostasis thrombosis chromogenic

diapharma

DiaPharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

Technical Support: 1.800.447.3846

ML-00-00998Rev01

Tissue-Specific Biomarkers for Liver Injury in Gene Therapy Research

Studying liver toxicity in gene therapy research?

liver toxicity in gene therapy

Emerging Exploratory Biomarkers for Drug Safety Studies

Improve Early DILI/DIKI Prediction Increased Tissue Specificity

  • K18 (M65®)
  • ccK18 (M30®)
  • L-FABP
  • α-GST
  • NGAL/Lipocalin-2
  • Osteopontin
  • Cystatin C
  • α-Klotho

liver toxicity in gene therapy

ELISAs for Drug-Induced Liver Injury (DILI)

Biomarker Sample Type Description Available Assay Product #
Keratin 18 (K18) Serum or plasma Highly specific biomarker for hepatocyte cell death (necrosis and apoptosis)

Peviva M65® ELISA

Peviva M65 EpiDeath® ELISA

P10020

P10040

Caspase-cleaved Keratin 18 (ccK18) Serum or plasma Highly specific specific biomarker for hepatocyte apoptosis Peviva M30 Apoptosense® P10011
Osteopontin (OPN) Serum or plasma Biomarker for hepatic inflammation and necrosis

Osteopontin

Osteopontin N-Half

DPG27158

DPG27258

Alpha Glutathione S-Transferase (a-GST) Serum or plasma Short half-life; sensitive to rapid changes in liver damage TECO® Alpha GST TE1056
Liver Fatty Acid Binding Protein (L-FABP, FABP1) Serum or plasma Sensitive marker for hepatic injury (leakage) Diapharma L-FABP DPGLFABP

Research use only in the U.S. and Canada. Not for use in diagnostic procedures.

NOGGIN MEF ELISA

Over 20 years of scientific expertise,
with support just a call or click away.

Visit diapharma.com

Diapharma Group, Inc. 8948 Beckett Rd, West Chester, OH 45069

ML-00-00615Rev01

NASH-TAG (Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis) Conference 2019

Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis

Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis
Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis
Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis

 


Diapharma will attend NASH-TAG 2019 this year. Please click here to schedule a meeting with us or email us directly.

Learn from the leading researchers in NASH and Liver Fibrosis at NASH-TAG 2019


NASH-TAG = THERAPEUTIC AGENTS for NON-ALCOHOLIC STEATOHEPATITIS


About NASH-TAG

The NASH-TAG Conference is designed to bring together clinicians and researchers in academia and the pharmaceutical industry for a focused interactive educational update highlighting the most relevant advances and challenges in the diagnosis and therapy of NASH and liver fibrosis. NASH-TAG 2019 will take place over two days providing attendees an understanding of current and future directions in diagnostic procedures, prospects and challenges in drug discovery and development for both NASH and liver fibrosis. Internationally renowned faculty will assist in the development of the educational content and will serve as faculty at the conference.


NASH-TAG Topics will include

  • MGL 3196 – a beta thyroid hormone receptor selective agonist
  • Aramchol – SCD1 modulator
  • NGM 282 – FGF19 construct
  • GS 9674 FXR – second generation FXR agonist
  • Selective PPAR modulators, hepatic and metabolic effects
  • Interactive Dialog on NASH Topics
  • Mitochrnodrial uncoupling as a pharmacological target in NASH
  • Extracellular vesticles as mediators of inflammation
  • Singnals form peclinical models and success of NASH trials
  • 3D Trissue modeling and precision cut liver slices: Will they help drug testing for NASH?
  • Barriers to overcome for reimbursement of NASH drugs
  • Lessons learned fromt he reimbursement of diabetes and CV drugs
  • Forecasting how the NASH market will develop in the US
  • Pros in clinical trials of NASH
  • Current and future trends in hepatic MRI using a background of cardiac MRI development
  • Assessing DILI in NASH trials
  • Genetic testing: Any use of sub phenotyping or risk stratification in clinical trials?
  • Update from EASL & AASLD
  • Understanding the methods of and need for CV risk assessment
  • Second harmonic generation fully quantitative histopathology assessment for NASH
  • GLP1R agonist compounds
  • GLP1 – glucagon receptor dual agonists
  • FGF21 – GLP1 dual agonism
  • Integrin antgonism as an anti-fibrotoic therapy
  • GPR40 and 84G cell coupled receptor modulators, BPI-4050
  • P2x7 – puringergic receptor antagoist

Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis
Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis
Therapeutic Agents for Non-Alcoholic Steatohepatitis and Liver Fibrosis

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