Assays for IVIG Testing

Posted: July 31, 2018

IVIG immunoglobulin testing assays for procoagulant contaminants

Manufacturers need reliable assays to test procoagulant contaminants in IVIG preparations, in order to reduce the risk of thromboembolic events. These products from Diapharma can be used for IVIG studies and for quality checks to ensure removal of thrombogenic agents.





Chromogenic kit for determination of low levels of FXIa in enriched or highly purified protein

  • Low interference – good for in-process and final testing of immunoglobulin preparations
  • Reagents comprise highly purified components and do not involve human plasma
  • Suitable for quantitative activity determination of FXIa as a contaminant in enriched and highly purified protein preparations such as IgG


IVIG immunoglobulin testing assays for procoagulant contaminants

Technothrombin® TGA


Fluorogenic assay for determination of thrombin generation

  • Give thrombotic potential a number
  • Ceveron® alpha automated analyzer for walk-away TGA
  • 96-well plate applications available

IVIG immunoglobulin testing assays for procoagulant contaminants



Chromogenic substrates

S-2302™ (S820340)

  • Prekallikrein, kallikrein inhibitors, FXII

S-2366™ (S821090)

  • FXI, APC
S-2238™ (S820324)

  • Thrombin, prothrombin, antithrombin

S-2288™ (S820852)

  • Broad spectrum of serine proteases



The Diapharma team brings a deep knowledge base and strong technical expertise to every customer interaction.

Questions about any product in our lineup? We’re just a click or phone call away. 800.526.5224 | |



All products are for research use only in the U.S. and Canada. ML-00-00362Rev01