ASCO 2018 – Thank you from Diapharma

Posted: July 26, 2018

 

Diapharma welcomed the opportunity to attend the ASCO 2018 Meeting. Read on to learn about our K18 assays for measuring apoptosis in anti-cancer drug research.

 

M30 Apoptosense®

M30 CytoDeath™

M65® ELISA

M65® EpiDeath

 

Biomarkers for measuring apoptosis and necrosis in cancer research

  • The M30 Apoptosense® CK18 research kit specifically detects caspase-cleaved CK18 (ccCK18) released from apoptotic tumor cells.

  • The M30 Apoptosense® ELISA assay is designed to be used together with the M65® ELISA which measures total CK18.

  • Determination of the ratio between caspase-cleaved to total CK18 released from dead cells offers a unique possibility to determine cell death mode (apoptosis or necrosis).

  • The M30 Apoptosense® CK18 and M65® CK18 kit are unique assays for studying tumor cell death during cancer research.

  • Read our brochure for complete details.

 

 

 

 

M30 Apoptosense® ELISA

(Prod. No P10011)

The M30 Apoptosense® ELISA measures the concentration of caspase-cleaved keratin 18 in human plasma, serum or cell culture supernatnts, reflecting the amount of apoptosis. The assay is based on the unique M30 antibody, which recognizes a neo-epitope of keratin 18 formed after caspase cleavage. The assay can be combined with the M65® ELISA for the analysis of cell death mode (necrosis or apoptosis).

All reagents are provided in a convenient ready-to-use format.

 

 

M30 CytoDeath™ ELISA

(Prod. No P10900)

The M30 CytoDeath™ ELISA offers a unique possibility to measure apoptotic cells in a multicellular spheroids and organ culture systems. The M30 CytoDeath™ ELISA is a product developed for cell culture applications, with a dynamic range and sensitivity suitable for in vitro work, making it a useful drug screening tool.

Similar to the M30 Apoptosense® ELISA, the M30 CytoDeath™ ELISA is based on the M30 antibody, detecting the caspase-cleaved keratin 18, All reagents are provided in a convenient ready-to-use format.

 

 

M65® ELISA

(Prod. No P10020)

The M65® ELISA measures soluble keratin 18 released from dying cells. It can be used to assess overall cell death, due to apoptosis or necrosis. The M65® ELISA is intended for human serum or plasma.

The M65® ELISA is primarily intended to be used together with the M30 Apoptosense® ELISA. When used together, the quantification of total cell death, apoptosis and necrosis is possible. as both assays are calibrated against the identical reference, the combination of the M30 Apoptosense® ELISA and the M65® ELISA allows determination of the relative contribution of apoptosis to total cell death. All reagents are provided in a convenient ready-to-use format.

 

 

M65 EpiDeath® ELISA

(Prod. No P10040)

The M65 EpiDeath® ELISA measures the concentration of soluble keratin 18 in the human plasma, serum and cell culture supernantants. The keratin 18 levels reflect the amount of total cell death, sue to apoptosis or necrosis.

The M65 EpiDeath® ELISA represents the next generation of keratin 18 positive biomarkers. All reagents are provided in a convenient ready-to-use format.

 

Visit diapharma.com for a complete list of products for oncology research.

 

RESEARCH USE ONLY IN THE U.S. AND CANADA

 

 

 

Diapharma Group, Inc.,  8948 Beckett Rd, West Chester, OH  45069

 ML-00-00364Rev01